Fig. 5.

Dopamine D1 receptor activation has no effect on local light-evoked GABAergic input to OFF bipolar cells. A: example GABAergic light-evoked inhibitory postsynaptic currents (L-IPSCs) in dark-adapted (black) and SKF38393 (SKF; dark gray) conditions in response to a 1-s, 25-µm bar, centered on the cell. Light gray bar indicates the end of stimulus presentation. B: average response charge transfer normalized (Norm.) to the dark-adapted response in SKF (n = 4) and light-adapted conditions (n = 7). C: same conditions as B for average response peak amplitude in SKF (n = 4) and light-adapted conditions (n = 7). D: same conditions as B for average percentage change in the transient component of the L-IPSC in SKF (n = 4) and light-adapted (n = 7) conditions. Brackets indicate comparison with the dark-adapted condition (dotted line). resp., Response. E: same conditions as A for example GABA_C L-IPSCs in dark-adapted (black) and SKF (dark gray) conditions. F: average response charge transfer and peak amplitude normalized to the dark-adapted response in SKF (n = 4) conditions. Light-adapted data were adapted from Mazade and Eggers (2016), Fig. 3, for comparison. Error bars are ±SE, and significance was calculated with the Wilcoxon rank sum test (***P < 0.001).