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. 2019 Feb 6;121(4):1232–1243. doi: 10.1152/jn.00448.2018

Table 1.

Average spontaneous (sIPSC) peak amplitudes and frequencies measured under different inhibitory conditions

Inhibition Dark-Adapted, pA +SKF, pA Dark-Adapted, pA Light-Adapted, pA Dark-Adapted, Hz +SKF, Hz Dark-Adapted, Hz Light-Adapted, Hz
Total inhibition 26.9 ± 5.5 17.5 ± 4.6* 23.2 ± 3.8 17.1 ± 2.3* 11.5 ± 5.8 3.2 ± 1.6* 17.0 ± 5.5 10.4 ± 3.4*
Isolated GABA 9.4 ± 1.3 9.4 ± 1.2 7.8 ± 1.2 0 ± 0 5.5 ± 4.3 0.8 ± 0.4* 0.7 ± 0.5 0 ± 0
Isolated glycine 21.4 ± 4.7 9.8 ± 1.8* 23.0 ± 5.3 17.9 ± 3.6* 9.3 ± 4.9 6.0 ± 3.6* 16.5 ± 7.3 13.3 ± 5.9*
Isolated glycine mIPSC 8.4 ± 1.9 7.5 ± 1.7 n.m. n.m. 3.3 ± 1.8 2.7 ± 1.7* n.m. n.m.

Values are means ± SE. There were no significant differences between dark-adapted averages of SKF38393 (SKF) and light adaptation experiments. Italics indicate raw data that were adapted from Mazade and Eggers (2013) and used to compare SKF and light-adapted conditions. Value of 0 means that all spontaneous inhibitory postsynaptic currents (sIPSCs) were abolished in the given condition.

*

Values that are significantly different when normalized to dark-adapted values for each cell (Wilcoxon tests). Exact P values are given in the text. mIPSC, miniature inhibitory postsynaptic current; n.m., not measured.