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. 2019 Apr 16;13(4):e0007263. doi: 10.1371/journal.pntd.0007263

Table 2. Exhaustiveness of case-area targeted interventions (CATIs) in response to cholera alerts from July 2013 to June 2017: Factors associated with the odds of CATI response to alerts (logistic mixed models).

Red and orange alerts Univariate analysis bc Multivariate analysis d
Responded Non-responded cOR
[95%-CI]
p-value aOR
[95%-CI]
p-value
Number of alerts (%) 3824 (49%) 4032 (51%)
Commune <0.0001 b
Department a 0.79 b
NGO responsible for CATI a 0.3 b
Commune, department and NGO random effects d <0.01
Alert level, red vs. orange a 2.22
[1.97–2.50]
<0.0001 c 2.52
[2.22–2.86]
<0.0001
Semester since mid-2013 a 1.42
[1.37–1.46]
<0.0001 c 1.43
[1.38–1.48]
<0.0001
Weekly UNICEF disbursements for CATIs, mean (SD; $10,000 USD) 12.9 (4.7) 12 (4.7) 1.06
[1.05–1.07]
<0.0001 c 1.01
[1.00–1.02]
0.22
Weekly accumulated rainfall in the commune, mean (SD; cm) 12.3 (14.2) 6.4 (9.6) 0.99
[0.98–1.00]
0.24 c 0.99
[0.97–1]
<0.05
Population of the commune, mean (SD; 10,000 inhabitants) 12.3 (14.2) 6.4 (9.6) 1.03
[0.68–1.81]
<0.01 c 1.01
[1–1.03]
0.11
OCV in the commune before or during the study period, number (%) 935 (24%) 1091 (27%) 1.11
[0.68–1.81]
0.67 c ND ND
Distance from the capital Port-au-Prince, mean (SD; 10 km) 14.5 (8.1) 16.8 (7.8) 1.02
[0.97–1.08]
0.44 c ND ND
Distance from the department capital, mean (SD; 10 km) 3.4 (2.7) 4.3 (3) 0.92
[0.86–0.98]
<0.01 c 0.94
[0.88–1]
0.06
Mountainous commune, no. of alerts (%) 1456 (38%) 1646 (41%) 1.01
[0.68–1.50]
0.96 c ND ND

Comparisons between responded and non-responded alerts were estimated using generalized linear mixed models with a binomial distribution.

a Response rates for each class are summarized in S3 Table provided as supplementary information

b For each of these univariate analyses, communes, departments or NGOs was modeled as a unique random effect variable.

c For these univariate analyses, communes, departments and NGOs were modeled as random effect variables, with communes nested within departments. Models provided a common P-value for both random effects.

d For the multivariate analysis, the model included communes, departments and NGOs as random effect variables, with communes nested within departments, and all fixed variables for which univariate P-value was <0.25 The model provided a common P-value for random effect variables.

SD, standard deviation; cOR, crude odds ratio; aOR, adjusted odds ratio; 95%-CI, 95% confidence interval; ND, no data (variables not included in the multivariate analysis).