Table 3. Intensity and quality of case-area targeted interventions (CATIs) in response to cholera alerts from July 2013 to June 2017: Factors associated with the incidence of complete CATIs per responded alert (negative-binomial mixed models).
| Univariate analysis bc | Multivariate analysis d | |||
|---|---|---|---|---|
| cIR [95%-CI] |
p-value | aIR [95%-CI] |
p-value | |
| Mean number of complete CATIs per responded alert, 5.1 (SD, 7.8) | ||||
| Commune | <0.0001 b | |||
| Department a | <0.0001 b | |||
| NGO responsible for CATI a | 0.98 b | |||
| Commune, department and NGO random effects d | <0.001 | |||
| Alert level, red vs. orange a | 1.72 [1.60–1.85] |
<0.0001 c | 1.85 [1.72–1.98] |
<0.0001 |
| Semester since mid-2013 a | 1.21 [1.18–1.23] |
<0.0001 c | 1.22 [1.20–1.25] |
<0.0001 |
| Weekly UNICEF disbursements for CATIs, mean (SD; $10,000 USD) | 1.03 [1.02–1.03] |
<0.0001 c | 1.00 [0.99–1.01] |
0.84 |
| Weekly accumulated rainfall in the commune, mean (SD; cm) | 1.00 [0.99–1.01] |
0.92 c | ND | ND |
| Population of the commune, mean (SD; 10,000 inhab.) | 1.02 [1.01–1.03] |
<0.0001 c | 1.02 [1.01–1.02] |
<0.0001 |
| OCV in the commune before or during the study period, number (%) | 1.18 [0.92–1.51] |
0.18 c | 0.99 [0.81–1.20] |
0.91 |
| Distance from the capital Port-au-Prince, mean (SD; 10 km) | 1.01 [0.98–1.04] |
0.4 c | ND | ND |
| Distance from the department capital, mean (SD; 10 km) | 0.96 [0.93–1.00] |
<0.05 c | 1.00 [0.97–1.02] |
0.77 |
| Mountainous commune, number of alerts (%) | 1.05 [0.85–1.29] |
0.65 c | ND | ND |
Comparison of the number of complete CATIs per responded alert was estimated using generalized linear mixed models with a negative-binomial distribution.
a Number of complete CATIs for each class are summarized in S3 Table provided as supplementary information.
b For each of these univariate analyses, communes, departments or NGOs was modeled as unique random effect variables.
c For these univariate analyses, communes, departments and NGOs were modeled as random effect variables, with communes nested within departments. Models provided a common p-value for both random effects.
d For all multivariate analysis, the model included communes, departments and NGOs as random effect variables, with communes nested within departments, and all fixed variables for which univariate p-value was <0.25 The model provided a common p-value for random effect variables.
SD, standard deviation; cIR, crude incidence ratio; aIR, adjusted incidence ratio; 95%-CI, 95% confidence interval; ND, no data (variables not included in the multivariate analysis).