Skip to main content
. 2005 Jan 24;2005(1):CD003980. doi: 10.1002/14651858.CD003980.pub2

O'Connell 2003.

Methods RCT. Random assignment to exercise (EX) or non‐exercise (NEX) group
Participants N = 11: EX = 5, NEX = 6
 Inclusion criteria: Kurtzke's EDDS‐score between 0 and 3, Relapse‐remission stage of MS, independently mobile and static in physical ability
 Exclusion criteria: changes in medication and physical status over last 3 months, need for aid/appliance for mobility Type MS: Relapsing‐remitting MS
 Disease duration (yr) ± SD (range): EX: 4.4 ± 4.5 , NEX: 4.3 ± 3.2
 Mean age (yr) ± SD (range): EX: 39.4 ± 6.5 , NEX :34.8 ± 12.8 
 % female: EX: 40, NEX: 30
 Mean EDSS‐score ± SD: EX: (1 ‐ 2), NEX: (1‐ 2.5)
Interventions Outpatient aerobic training sessions in circuit style performed in classes.2x1h sessions in class and one session alone per week for a period of 3 months.
 controls: No exercise training
Outcomes MGET, Borg's Perception of Exertion, Timed Walk (50m.), Cadence, MSIS and FAMS. Assessments at baseline and after 3 months
Notes Drop outs: 2: 2 subjects (EX) were excluded due to a new relapse.
 Trial presented at the World Confederation for Physical Therapy 2003 in Barcelona. Part of a continuing trial