20. Absolute event rates: opioids versus active pharmacological comparator.

		Opioid				Active comparator
		Number of participants		Event rate (%)		Number of participants		Event rate (%)
Analysis	Adverse event	With AE	Total	Average	95% CI	With AE	Total	Average	95% CI
1.1	Any adverse event	454	785	57.8	54.4 to 61.3	381	798	47.7	44.3 to 51.2
1.2	Any serious adverse event	5	54	9.3	1.5 to 17	1	54	1.9	0 to 5.4
1.3	Withdrawals due to adverse events	185	1201	15.4	13.4 to 17.4	56	1174	4.8	3.6 to 6

AE: adverse event
 CI: confidence interval