for the main comparison.
Dexibuprofen compared with placebo for acute postoperative pain | ||||||
Patient or population: Adults with moderate or severe acute postoperative pain Settings: Community or hospital Intervention: Dexibuprofen 200 mg or 400 mg Comparison: Placebo | ||||||
Outcomes | Probable outcome with |
NNT or NNH and/or relative effect (95% CI) |
No of studies, attacks, events |
Quality of the evidence (GRADE) |
Comments | |
comparator | intervention | |||||
At least 50% of maximum pain relief over 4 to 6 hours | Insufficent data | Very low | Quality of evidence very low because of small numbers of studies and participants | |||
Participants with at least 1 adverse event | No data | Very low | ||||
Participants with a serious adverse event | No serious adverse events | Very low | ||||
Deaths | No deaths | Very low | ||||
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. |