for the main comparison.

Dexibuprofen compared with placebo for acute postoperative pain
Patient or population: Adults with moderate or severe acute postoperative pain Settings: Community or hospital Intervention: Dexibuprofen 200 mg or 400 mg Comparison: Placebo
Outcomes	Probable outcome with		NNT or NNH and/or relative effect (95% CI)	No of studies, attacks, events	Quality of the evidence (GRADE)	Comments
	comparator	intervention
At least 50% of maximum pain relief over 4 to 6 hours	Insufficent data				Very low	Quality of evidence very low because of small numbers of studies and participants
Participants with at least 1 adverse event	No data				Very low
Participants with a serious adverse event	No serious adverse events				Very low
Deaths	No deaths				Very low
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate.