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. Author manuscript; available in PMC: 2019 Apr 26.
Published in final edited form as: Handb Clin Neurol. 2018;147:105–123. doi: 10.1016/B978-0-444-63233-3.00009-9

Figure 2. Relationship of repeat length to disease features in spinocerebellar ataxia type 3 (SCA3).

Figure 2.

Normal CAG repeat length in SCA3 is 12 to ~44, with disease repeats ranging from ~60–87. Clinical subtypes 1 (dystonia), 2 (ataxia), and 3 (weakness) tend to be associated with the range of indicated repeat lengths. Rare intermediate repeat lengths may be associated with restless legs syndrome.