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. Author manuscript; available in PMC: 2019 Apr 26.
Published in final edited form as: Arch Toxicol. 2016 Dec 18;91(8):2837–2847. doi: 10.1007/s00204-016-1908-3

Table 3.

Rates of inhibition by carbamylating agents

Carbamylating agent kr (M−1 min−1)
Neostigmine 1.3±0.2 × 105
Physostigmine 0.32± 0.02 × 105
Pyridostigmine 0.10± 0.01 × 105
Carbaryl 0.00064± 0.00008 × 105

kr values (bimolecular rate constants) were calculated from at least 4 different carbamate concentrations and reported as mean± 95% confidence intervals from at least 2 independent experiments (technical and biological replicates). Raw data are shown in Fig. S2