*Defined as the presence of both right ventricular dysfunction and myocardial injury.
Accumulation of factors indicating poor prognosis (right side of the Figure) may alter the risk-benefit assessment in favor of thrombolytic therapy before the development of hemodynamic instability.
Abbreviations: RV, right ventricle; bpm, beats per minute; DVT, deep vein thrombosis; ICU, intensive care unit.