Table 3.
Name of trial | Adverse event | Experimental arm (N) | Control arm (N) |
GCLLSG CLL 8 | |||
Cytokine release syndrome grade 3/4 | 1/404 | 0/396 | |
Haematological toxicity grade 3/4 | 225/404 | 157/396 | |
Leukocytopenia grade 3/4 | 97/404 | 48/396 | |
Tumour lysis syndrome grade 3/4 | 1/404 | 2/396 | |
Autoimmune haemolytic anaemia | 22/404 | 27/396 | |
Infection | 103/404 | 85/396 | |
REACH | |||
Febrile neutropenia grade 3/4 | 33/274 | 32/272 | |
Granulocytopenia grade 3/4 | 18/274 | 12/272 | |
Hepatitis B grade 3/4 | 0/274 | 5/272 | |
Pancytopenia grade 3/4 | 9/274 | 13/272 | |
Pneumonia | 15/274 | 17/272 |