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. 2017 Nov 3;2017(11):CD011564. doi: 10.1002/14651858.CD011564.pub2

Xing 2013.

Methods Randomised clinical trial with parallel group design (3 groups).
Participants 75 participants (17% women), aged 28 to 65 years, mean age 48 years, undergoing liver transplantation.
Inclusion criteria: primary liver transplant recipients.
Exclusion criteria: history of corticosteroid, anticonvulsant, or vitamin D intake; renal disease.
Interventions Intervention 1: calcitriol 0.25 μg/day + calcium gluconate (n = 25).
Intervention 2: calcium gluconate (n = 25).
Control: placebo (n = 25).
For 1 month.
Outcomes Outcomes reported in abstract of publication:
Primary outcomes: acute cellular rejection rate at 1 month' post transplant.
Secondary outcomes: none stated.
Stated aim of study To investigate effects of calcitriol on acute cellular rejection rate of liver transplant recipients.
Notes Study sponsored by a grant from Shanghai Nature Science Fund project and a grant from Science and Technology Department of Shanghai. Additional information received through personal communication with the authors on 13 February 2014.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method of sequence generation not specified.
Allocation concealment (selection bias) Unclear risk Method used to conceal allocation not described so that intervention allocations may have been foreseen in advance of, or during, enrolment.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Insufficient information to permit judgement of 'low risk' or 'high risk'.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Insufficient information to permit judgement of 'low risk' or 'high risk'.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Missing data unlikely to make treatment effects depart from plausible values.
Selective reporting (reporting bias) Unclear risk Unclear whether all predefined and clinically relevant and reasonably expected outcomes were reported.
For‐profit bias Low risk Trial appeared to be free of industry sponsorship or other type of for‐profit support that could manipulate the trial design, conductance, or trial results.
Other bias Low risk Trial appeared to be free of other factors that could put it at risk of bias.