Mahesh Kumar 2013.

Methods	Design: randomised, double‐blind, parallel‐group, controlled trial
Participants	Setting: inpatient ward of a teaching hospital in India Assessed for eligibility: 78 Randomised: 20 hypertonic saline group; 20 normal saline group Completed: 20 hypertonic saline group; 20 normal saline group Gender (male): 62.5% Age (mean ± SD): 5.9 ± 3.8 months Inclusion criteria: children aged < 2 years, hospitalised with acute bronchiolitis defined as the first episode of lower respiratory tract infection with wheeze and having a moderate respiratory distress with clinical severity score between 4 and 8 Exclusion criteria: children with pre‐existing cardiac disease, previous wheezing episodes, severe disease (clinical severity score > 8) requiring mechanical ventilation (SaO₂ < 85% on room air, cyanosis, obtunded consciousness, and/or progressive respiratory failure)
Interventions	Intervention group: nebulised 3% hypertonic saline (3 mL) plus salbutamol (0.15 mg/kg) Control group: nebulised 0.9% normal saline (3 mL) plus salbutamol (0.15 mg/kg) The medication was given via a nebuliser driven by oxygen flow at 5 to 6 L/min, every 6 h until ready for discharge.
Outcomes	Length of hospital stay Wang clinical severity score Number of add‐on nebulisation
Notes	Virological identification not available.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated randomisation
Allocation concealment (selection bias)	Unclear risk	No details provided.
Blinding (performance bias and detection bias) All outcomes	Unclear risk	The trial was stated as double‐blind, but no details were provided.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No withdrawals reported.
Selective reporting (reporting bias)	Low risk	All predefined outcomes reported.
Other bias	Low risk	No other bias found.