NCT02029040.

Methods	Randomised, double‐blind, parallel‐group, controlled trial
Participants	Children aged 2 to 12 months, presenting to ED with a diagnosis of bronchiolitis (RDAI score = 6) defined as the first episode of wheezing or crackles, or both in a child younger than 12 months who has physical findings of a viral respiratory infection and there is no other explanation for the wheezing and/or crackles
Interventions	Nebulised 3% hypertonic saline (3 mL) versus nebulised 0.9% normal saline (3 mL) A single dose of study solution was given.
Outcomes	Primary outcomes: Respiratory assessment change score (RACS) at 15 minutes and 1 hour Secondary outcomes: Rate of hospitalisations at 24 hours Return to ED within 7 days following discharge
Notes	Starting date: December 2013 Completion of data collection: December 2014 Last updated: 3 May 2016 Contact information: Mohamed Badawy, MD, University of Texas Southwestern Medical Center