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. 2013 Dec 12;2013(12):CD008742. doi: 10.1002/14651858.CD008742.pub2

Spence 1995.

Methods RCT; no info on randomisation procedure
Participants Chronic (> 10 months) complaints, upper extremity (non‐specific) associated with repetitive tasks in the workplace; n = 48 (40 women)
Interventions EMG biofeedback (EMG): auditory feedback on muscle tension levels + home‐based assignments; n = 12
EMG + relaxation (CO): combined treatment of EMG and ART; n = 12
Relaxation training (ART): consists of a range of relaxation techniques + home‐based assignments; n = 12
Waiting list controls (WCL): n = 12
 
Eight weeks. Follow‐up six months 
Outcomes Pain (Whimpy, Likert, PBQ), depression (BDI), ADL
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Unclear randomisation procedure
Allocation concealment (selection bias) Unclear risk Unclear whether allocation was concealed
Blinding of participants? Unclear risk Unclear
Blinding of caregivers? Unclear risk Unclear
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Unclear whether outcome assessment was blinded
Incomplete outcome data (attrition bias) 
 All outcomes ‐ <20% drop‐outs? High risk Three dropouts at short term; eight at long term (> 20%)
Incomplete outcome data (attrition bias) 
 All outcomes ‐ ITT analysis performed? High risk No ITT analysis
Selective reporting (reporting bias) Unclear risk No protocol
Similarity of baseline characteristics? High risk Baseline groups were regarded as not comparable
Co‐interventions avoided? Unclear risk Unclear whether co‐interventions were avoided
Compliance acceptable ? Unclear risk Unclear compliance
Timing outcome assessment comparable? Low risk Timing was comparable