Gaur 2008.
Methods | Parallel RCT. | |
Participants | Age: 18 to 60 years. Location: emergency department of a tertiary referral centre in India. Acute asthma and FEV1 < 30% predicted. Intervention: 30. Control: 30. |
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Interventions | Intervention: nebulised similarly using isotonic MgSO₄ (3 mL of 3.2 g%) as a vehicle ‒ unsure if this is “Nebulized salbutamol and ipratropium”. Control: nebulised salbutamol and ipratropium using isotonic saline as a vehicle thrice at 20‐min intervals. |
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Outcomes | FEV% predicted at 120 minutes, pooled discharge rate proportion of groups attaining PEF > 60% predicted and relief in dyspnoea at 30, 60, 90, 120 min). | |
Notes | Abstract only. Funding: not reported. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomised. |
Allocation concealment (selection bias) | Unclear risk | Not stated. |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Single blind – no further details. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Single blind – no further details. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Not stated. |
Selective reporting (reporting bias) | High risk | 1 outcome partially reported and not significant. Abstract only. |