1. Study results for Santana‐Sosa 2012.
| Variable | Group | Pre‐training | Post‐training | Detraining | P value (group x time) | Comments |
| Age (mean (SE)) years | Intervention | 11 (3) | ‐ | ‐ | ‐ | |
| Control | 10 (2) | ‐ | ‐ | ‐ | ||
| Sex (% boys) | Intervention | 55 | ‐ | ‐ | ‐ | |
| Control | 64 | ‐ | ‐ | ‐ | ||
| VO2 peak (mean (95% CI)) ml/min per kg body weight | Intervention | n.a. | 3.9 (1.8 to 6.1) | ‐3.4 (‐5.7 to 1.7) | 0.036 | Significantly higher in controls at baseline (P = 0.023). Data were presented in a figure in the original publication. |
| Control | n.a. | ‐2.2 (‐5.3 to 0.1) | ‐0.7 (‐4.4 to 5.9) | |||
| Leg press (mean (95% CI)) kg | Intervention | n.a. | 24.9 (14.3 to 34.4) | ‐1.0 (‐4.1 to 3.3) | < 0.001 | Data are reported in a figure in the original publication. Significantly higher in controls at baseline (P = 0.014). |
| Control | n.a. | n.a. | n.a. | |||
| Bench press (mean (95% CI)) kg | Intervention | n.a. | 10.5 (7.0 to 14.0) | ‐1.2 (‐3.6 to 3.0) | < 0.001 | Significantly higher in controls at baseline (P = 0.007). Data presented in a figure in the original publication. |
| Control | n.a. | n.a. | n.a. | |||
| Seated row (mean (95% CI)) kg | Intervention | n.a. | 12.7 (9.2 to 16.0) | ‐0.2 (‐3.6 to 3.2) | < 0.001 | Significantly higher in controls at baseline (P = 0.009). Data presented in a figure in the original publication. |
| Control | n.a. | n.a. | n.a. | |||
| Oxygen saturation at peak exercise (mean (SE)) | Intervention | 94.9 (0.9)% | 95.6 (0.8)% | 94.5 (1.2)% | n.a. | |
| Control | 95.7 (0.5)% | 96.4 (0.4)% | 96.1 (0.5)% | |||
| FEV1 (mean (SE)) litres | Intervention | 1.87 (0.24) | 1.94 (0.23) | 1.90 (0.25) | 0.769 | |
| Control | 1.77 (0.17) | 1.87 (0.15) | 1.79 (0.19) | |||
| FVC (mean (SE)) litres | Intervention | 2.41 (0.24) | 2.49 (0.25) | 2.56 (0.29) | 0.920 | |
| Control | 2.29 (0.19) | 2.36 (0.20) | 2.40 (0.24) | |||
| PImax (mean (SE)) cm H2O | Intervention | 64.0 (5.5) | 69.8 (6.8) | 75.2 (6.2) | 0.797 | |
| Control | 61.5 (6.9) | 72.2 (7.2) | 76.4 (7.5) | |||
| HRQoL score ‐ children's report (median (range)) | Intervention | 696 (495 ‐ 741) | 719 (550 ‐ 734) | ‐ | 0.257 | HRQoL was assessed before and after the intervention. P value for comparison pre versus post‐training. |
| Control | 649 (578 ‐ 768) | 638 (461 ‐ 791) | ‐ | |||
| HRQoL score ‐ parents' report (median (range)) | Intervention | 896 (688‐1011) | 889 (811 ‐ 973) | ‐ | 0.143 | HRQoL was assessed before and after the intervention. |
| Control | 911 (842 ‐ 1028) | 978 (684 ‐ 1059) | ‐ | |||
| Weight (mean (SE)) kg | Intervention | 39.9 (3.5) | 40.5 (3.4) | 41.4 (3.4) | 0.723 | |
| Control | 34.0 (2.6) | 35.1 (2.8) | 36.2 (3.0) | |||
| BMI (mean (SE)) kg/m² | Intervention | 18.4 (1.0) | 18.3 (0.7) | 18.5 (0.7) | 0.959 | |
| Control | 17.2 (0.8) | 17.1 (0.8) | 17.4 (0.9) | |||
| Fat‐free mass (mean (SE)) % | Intervention | 78.1 (2.7) | 79.4 (2.8) | 78.8 (2.9) | 0.115 | |
| Control | 81.1 (2.5) | 80.9 (2.1) | 81.1 (2.2) | |||
| Body fat (mean (SE)) % | Intervention | 21.9 (2.7) | 20.6 (2.8) | 21.2 (2.9) | 0.115 | |
| Control | 18.9 (2.5) | 19.1 (2.1) | 18.9 (2.2) | |||
| Compliance with physical training (mean (SE)) % | Intervention | ‐ | 95.1 (7.4) | ‐ | ‐ ‐ |
73% of children completed all training sessions. |
| Control | ‐ | ‐ | ‐ | |||
| Adverse effects | Intervention | ‐ | ‐ | ‐ | ‐ | No adverse effects occurred during training or maximal exercise testing. |
| Control | ‐ | ‐ | ‐ |
BMI: body mass index CI: confidence interval FEV1: forced expiratory volume in one second FVC: forced vital capacity HRQoL: health‐related quality of life n.a.: not applicable PImax: maximum inspiratory mouth pressure SE: standard error VO2 peak: peak oxygen consumption