Turchetta 1991.
| Methods | Design: single‐centre, parallel RCT; hospital admission for routine assessment of clinical condition. Inclusion criteria: not specified. Exclusion criteria: not specified. |
|
| Participants | 12 children with CF, 8 males, mean age 12.3 years. No group demographics available. | |
| Interventions | Short‐term aerobic study.
Group 1: 20 min running or treadmill per day for 2 weeks. Group 2: normal hospital treatment. |
|
| Outcomes | Included in this study were: FEV1 and FVC. | |
| Notes | This study has only been reported in a single abstract and therefore the information is limited. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Described as randomised, but no details given for sequence generation. |
| Allocation concealment (selection bias) | Unclear risk | Not discussed. |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not possible to blind participants to intervention. Unclear whether personnel blinded. |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Unclear whether outcome assessors blinded. |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | No details of dropouts or whether intention‐to‐treat analysis had been used. |
| Selective reporting (reporting bias) | Unclear risk | This is an abstract so unable to assess if all outcome used in methods were reported in results. Data were reported for all time points. |
| Other bias | Unclear risk | Do not state inclusion or exclusion criteria, nor do they describe the methods of statistical analysis used. |
BMI: body mass index CF: cystic fibrosis CFRD: cystic fibrosis‐related diabetes FEF25‐75: forced expiratory flow 25‐75% FEV1: forced expiratory volume at one second FRC: functional residual capacity FVC: forced vital capacity HRQoL: health‐related quality of life IGT: impaired glucose tolerance MP: mean power MVV: maximal voluntary ventilation PFS: progression‐free survival PImax: maximum inspiratory mouth pressure PP: peak power Raw: airways resistance RCT: randomised controlled trial RER: respiratory exchange ratio RR: respiratory rate RV: residual volume SaO2: oxygen saturation SD: standard deviation SEM: standard error of the mean SGAW: specific airways conductance TLC: total lung capacity VE: minute ventilation VO2 peak: peak oxygen consumption VCO2: carbon dioxide production VO2: oxygen uptake W: watt WAnT: Wingate Anaerobic Test 6MWT: six‐minute walk test