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. 2017 Nov 9;2017(11):CD011770. doi: 10.1002/14651858.CD011770.pub2

Comparison 13. Postoperative pain intensity at 24 hours: intravenous dexamethasone versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Postoperative pain intensity at 24 hours 5 257 Mean Difference (IV, Random, 95% CI) ‐1.26 [‐2.23, ‐0.29]
2 Postoperative pain intensity at 24 hours: additive versus no additive subgroups 5 257 Mean Difference (IV, Random, 95% CI) ‐1.26 [‐2.23, ‐0.29]
2.1 Additive 1 49 Mean Difference (IV, Random, 95% CI) ‐0.90 [‐2.75, 0.95]
2.2 No additive 4 208 Mean Difference (IV, Random, 95% CI) ‐1.33 [‐2.48, ‐0.18]
3 Postoperative pain intensity at 24 hours: high‐ versus low‐dose dexamethasone subgroups 5 257 Mean Difference (IV, Random, 95% CI) ‐1.26 [‐2.23, ‐0.29]
3.1 High‐dose dexamethasone 4 217 Mean Difference (IV, Random, 95% CI) ‐1.31 [‐2.54, ‐0.07]
3.2 Low‐dose dexamethasone 1 40 Mean Difference (IV, Random, 95% CI) ‐1.1 [‐2.49, 0.29]
4 Postoperative pain intensity at 24 hours: high/unclear versus low risk of bias subgroups 5 257 Mean Difference (IV, Random, 95% CI) ‐1.26 [‐2.23, ‐0.29]
4.1 High/unclear risk of bias 1 40 Mean Difference (IV, Random, 95% CI) ‐1.1 [‐2.49, 0.29]
4.2 Low risk of bias 4 217 Mean Difference (IV, Random, 95% CI) ‐1.31 [‐2.54, ‐0.07]