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. 2017 Nov 9;2017(11):CD011770. doi: 10.1002/14651858.CD011770.pub2

Comparison 21. Postoperative pain intensity at 12 hours: perineural versus intravenous dexamethasone.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Postoperative pain intensity at 12 hours 3 217 Mean Difference (IV, Random, 95% CI) ‐1.01 [‐1.51, ‐0.50]
2 Postoperative pain intensity at 12 hours: low‐ versus high‐dose dexamethasone subgroups 3 217 Mean Difference (IV, Random, 95% CI) ‐1.01 [‐1.51, ‐0.50]
2.1 Low‐dose dexamethasone 2 139 Mean Difference (IV, Random, 95% CI) ‐1.04 [‐1.60, ‐0.47]
2.2 High‐dose dexamethasone 1 78 Mean Difference (IV, Random, 95% CI) ‐0.90 [‐2.01, 0.21]
3 Postoperative pain intensity at 12 hours: high/unclear versus low risk of bias subgroups 3 217 Mean Difference (IV, Random, 95% CI) ‐1.01 [‐1.51, ‐0.50]
3.1 HIgh/unclear risk of bias 2 139 Mean Difference (IV, Random, 95% CI) ‐1.04 [‐1.60, ‐0.47]
3.2 Low risk of bias 1 78 Mean Difference (IV, Random, 95% CI) ‐0.90 [‐2.01, 0.21]