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. 2017 Nov 9;2017(11):CD011770. doi: 10.1002/14651858.CD011770.pub2

Comparison 22. Postoperative pain intensity at 24 hours: perineural versus intravenous dexamethasone.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Postoperative pain intensity at 24 hours 5 309 Mean Difference (IV, Random, 95% CI) ‐0.79 [‐1.51, ‐0.07]
2 Postoperative pain intensity at 24 hours: additive versus no additive subgroups 5 309 Mean Difference (IV, Random, 95% CI) ‐0.79 [‐1.51, ‐0.07]
2.1 Additive 1 50 Mean Difference (IV, Random, 95% CI) ‐1.70 [‐3.32, ‐0.08]
2.2 No additive 4 259 Mean Difference (IV, Random, 95% CI) ‐0.64 [‐1.41, 0.13]
3 Postoperative pain intensity at 24 hours: low‐ versus high‐dose dexamethasonesubgroups 5 309 Mean Difference (IV, Random, 95% CI) ‐0.79 [‐1.51, ‐0.07]
3.1 Low‐dose dexamethasone 2 139 Mean Difference (IV, Random, 95% CI) ‐0.95 [‐2.01, 0.11]
3.2 High‐dose dexamethasone 3 170 Mean Difference (IV, Random, 95% CI) ‐0.68 [‐1.95, 0.59]
4 Intensity of postoperative pain at 24 hours: high/unclear risk of bias versus low risk of bias subgroups 5 309 Mean Difference (IV, Random, 95% CI) ‐0.79 [‐1.51, ‐0.07]
4.1 High/unclear risk of bias 2 139 Mean Difference (IV, Random, 95% CI) ‐0.95 [‐2.01, 0.11]
4.2 Low risk of bias 3 170 Mean Difference (IV, Random, 95% CI) ‐0.68 [‐1.95, 0.59]