Dar 2013.
Methods | Parallel group RCT. | |
Participants | In India, 80 ASA class I‐II participants aged 20‐50 years undergoing upper limb surgery with supraclavicular brachial plexus block were included. No exclusion criteria were stated. | |
Interventions |
Block All participants received supraclavicular brachial plexus block with ropivacaine 0.5% 30 ml using landmarks. Dexamethasone/placebo Dexamethasone group: dexamethasone 8 mg perineurally. Placebo group: normal saline 2 ml perineurally. Intraoperative anaesthesia/analgesia None described. Postoperative analgesia Diclofenac IM 75 mg was administered when the VAS was greater than 4. |
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Outcomes |
Outcomes of interest for the review Duration of sensory block defined as the time interval between the end of local anaesthetic administration and complete resolution of sensory block (normal sensation). Duration of motor block defined as the time interval between the end of local anaesthetic administration and the recovery of full power in the relevant muscle group. Incidence of adverse events including hypotension (a 20% decrease in relation to baseline), bradycardia (heart rate less than 50 beats per minute), hypoxaemia (SpO2 < 90%) and nausea and vomiting. Other outcomes Onset of sensory block defined as the time interval between the end of local anaesthetic administration and complete sensory block. Onset of motor block defined as the time interval between the end of local anaesthetic administration and the time of no movement in the relevant group. Quality of intraoperative analgesia judged by the investigator on a 4‐point scale. |
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Notes | Funding: none. Conflicts of interest: none. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No indication of how random sequence was generated. |
Allocation concealment (selection bias) | Low risk | Sealed envelopes were used to conceal treatment allocation. |
Blinding of participants (detection bias) | Unclear risk | No indication whether participants were blinded. |
Blinding of personnel (detection bias) | Unclear risk | No indication whether personnel were blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No indication whether outcome assessors were blinded. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No missing outcome data. |
Selective reporting (reporting bias) | Low risk | No protocol available. All outcomes reported as described in the methods section. |
Other bias | Low risk | Appears to be free of any other bias. |