Dawson 2016.

Methods	Parallel group RCT.
Participants	In Australia, 90 ASA class I‐III participants undergoing metatarsal osteotomy with ankle block were included. Participants classified as ASA greater than III, those less than 18 years old, those with coagulopathy, sepsis or infection at the operative site, allergy to ropivacaine, those taking regular opioids or glucocorticoids were excluded from the study.
Interventions	Block All participants received ankle block with ropivacaine 0.75% 20 ml with ultrasound guidance. Dexamethasone/placebo Perineural dexamethasone group: dexamethasone 8 mg perineurally and normal saline 2 ml intravenously. Intravenous dexamethasone group: dexamethasone 8 mg intravenously and normal saline 2 ml mixed with the block solution. Placebo group: normal saline 2 ml mixed with the block solution and 2 ml intravenously. Intraperative anaesthesia/analgesia None reported. Postoperative analgesia Paracetamol 665 mg. Oxycodone 5 mg. Tamadol 50 mg.
Outcomes	Outcomes of interest for the review Postoperative opioid consumption. Incidence of PONV. Other outcomes Pain score when block wore off, at seven days after surgery and maximum pain score during study period. Duration of block defined as the time when sensation and movement returned to normal.
Notes	Funding: none. Conflicts of interest: none.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random sequence was computer‐generated.
Allocation concealment (selection bias)	Low risk	Treatment allocation was concealed in sealed envelopes.
Blinding of participants (detection bias)	Unclear risk	No indication whether participants were blinded.
Blinding of personnel (detection bias)	Low risk	Assume personnel were blinded since study drugs were prepared by a nurse not involved in the study and all study drugs were similar in appearance.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No indication whether outcome assessors were blinded.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing outcome data.
Selective reporting (reporting bias)	Low risk	No protocol available but all outcomes reported as stated in the methods section.
Other bias	Low risk	Appears to be free of any other bias.