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. 2017 Nov 9;2017(11):CD011770. doi: 10.1002/14651858.CD011770.pub2

Golwala 2009.

Methods Parallel group RCT.
Participants In India, 60 ASA class I‐II participants undergoing elective or emergency upper limb surgery with supraclavicular brachial plexus block were included. Participants with a history or uncontrolled diabetes, renal or liver disease, circulatory instability, pregnancy, peptic ulcer disease, allergy to local anaesthetics or receiving long‐term steroid therapy were excluded.
Interventions Block
All participants underwent landmark‐guided supraclavicular block with lidocaine 2 % 15 ml + bupivacaine 0.5% 15 ml + adrenaline 1:200,000
Dexamethasone/placebo
Dexamethasone group: dexamethasone 8 mg perineurally.
Placebo group: normal saline 2 ml perineurally.
Intraoperative anaesthesia/analgesia
Midazolam IV 1 mg was administered after the block.
Postoperative analgesia
Diclofenac IM 1.5 mg/kg was administered when VAS was 5 or greater.
Outcomes Outcomes of interest for the review
Intensity of postoperative pain measured on an 11‐point VAS every 3 hours after surgery.
Duration of sensory block defined as the time from drug injection in brachial plexus to VAS = 5.
Incidence of side effects in the intraoperative and postoperative period.
Other outcomes
Onset of sensory block defined as dull sensation along any nerve distrubution.
Onset of motor block defined as the time when the patient felt heaviness on abduction of arm at the shoulder.
Notes Duration of block was reported as a range without any measure of central tendency. Pain scores were reported up to six hours in the placebo group and 15 hours in the dexamethasone group, therefore the data for this study could not be included in the meta‐analysis. Incidence of side effects was the only outcome that could be included in the analysis.
Funding: no information provided.
Conflicts of interest: no information provided.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No indication of how random sequence was generated.
Allocation concealment (selection bias) Unclear risk No indication of how treatment allocation was concealed.
Blinding of participants (detection bias) Unclear risk No indication whether participants were blinded.
Blinding of personnel (detection bias) Unclear risk No indication whether personnel were blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No indication whether outcome assessors were blinded.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing outcome data.
Selective reporting (reporting bias) High risk No protocol available. Pain scores were reported up to six hours in the placebo group and up to 15 hours in the dexamethasone group.
Other bias Low risk Appears to be free of any other bias.