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. 2017 Nov 13;2017(11):CD010323. doi: 10.1002/14651858.CD010323.pub3

Jamison 2010.

Study characteristics
Methods Randomised trial, standard medical care control
Assessments at baseline and 6 months
Participants Chronic pain patients with a history or risk of opioid misuse. All participants had chronic back or neck pain.
42 patients were randomised; CBT (n = 21), standard medical care (n = 21)
Female 20; male 22
Mean age = 46.79 years, SD = 7.27 years
Interventions CBT for prevention of opioid misuse: group and individual sessions were delivered to participants. Treatment was composed of 5 components; electronic monthly diaries, monthly urine screens, monthly completion of the Opioid Compliance Checklist, monthly group education sessions and worksheets, individual motivational compliance counselling. Groups and individual sessions included enhancing and maintaining motivation to avoid illicit substance use, coping with urges, problem solving, and lifestyle balance. Participants were provided with discussions round risk factors, motivational counselling, homework, and completed a monthly opioid compliance checklist. Treatment lasted 6 months.
Standard medical care: no description provided
Outcomes Prescribed medication use: no measure of prescription. Measures of desire for opioids and Current Opioid Misuse Measure were included.
Pain: BPI, pain severity subscale
Psychological function: HADS
Physical function: BPI, pain interference subscale, Pain Disability Index
Notes The study was supported in part by an investigator‐initiated grant from End Pharmaceuticals, Chadds Ford, PA and Grants R21 DA024298, Jamison PI and K23DA020682 Wasan PI from the National Institute on Drug Abuse of the National Institutes of Health, Bethesda, MD, and the ARthritis Foundindation (Wasan)
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk "...assignment to treatment group based on a randomized number list created before the start of the study. Subjects were assigned to their group in the order that they entered into the study"
Allocation concealment (selection bias) Unclear risk Not described
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk No description provided
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Attrition is described but analyses of differences between completers and non‐completers was not conducted.
Selective reporting (reporting bias) High risk Post‐treatment means and SDs are not provided for all measures.
Size High risk 21 per group