Bucknall 1981.
Methods |
RCT Methods to control for contributory patient factors: none described |
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Participants |
Age: Group 1 (mean): 53.3 years Group 2 (mean): 50.5 years Gender: Group 1: 53.8% female Group 2: 61.5% female Type of incision: Group 1: midline 37.7%, paramedian 62.3% Group 2: midline 41.3%, paramedian 58.6% Type of surgery: Group 1: emergent 18.8%; "bowel surgery" 43.4%; malignancy 26.4% Group 2: emergent 17.3%; "bowel surgery" 39.4%; malignancy 20.2% Contamination classification of included participants: information not provided Pre‐operative antibiotic use: information not provided Prognostic patient factors: information not provided Inclusion criteria: all adult patients admitted to 1 hospital who underwent laparotomy through vertical incisions in the year 1979 Exclusion criteria: none described |
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Interventions |
Comparisons reported: Group 1 Suture: nylon (monofilament, non‐absorbable) Suturing technique: continuous Closure method: mass Group 2: Suture: PGA (multifilament, fast absorbable) Suturing technique: continuous Closure method: mass Surgeon characteristics: Group 1: consultant 32.1%; senior resident 44.3%; other resident 23.6% Group 2: consultant 26.0%; senior resident 49.0%; other resident 25.0% |
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Outcomes |
Incisional hernia: no definition provided Follow‐up duration: 8.3 months in nylon group, 8.5 months in PGA group Wound infection: no definition provided Wound dehiscence: "total wound disruption" Suture sinus or fistula: no definition provided |
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Notes | Hernia data not included in analysis due to inadequate follow‐up duration; other outcomes included | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "In 1979, all adult patients in the Professorial Surgical Unit at Westminster Hospital who underwent laparotomy through vertical incisions were randomised, by means of random number cards, into two groups." |
Allocation concealment (selection bias) | Unclear risk | No information provided |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | No information provided |
Incomplete outcome data (attrition bias) All outcomes | Low risk | < 10% loss to follow‐up (4/110 in group 1, 2/106 in group 2) |
Selective reporting (reporting bias) | Low risk | There was no evidence of selective reporting |
Other bias | Low risk | The study appears to be free of other sources of bias |