Cameron 1980.
Methods |
RCT Methods to control for contributory patient factors: none described |
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Participants |
Age: not reported Gender: Group 1: 54.5% female Group 2: 51.1% female Type of incision: Group 1: midline 34.1%, paramedian 65.9% Group 2: midline 34.4%, paramedian 65.6% Type of surgery: Group 1: emergency 17.4% Group 2: emergency 22.2% Contamination classification of included participants: Group 1: contaminated 7.2% Group 2: contaminated 10.5% Pre‐operative antibiotic use: no information provided Prognostic patient factors: Group 1: corticosteroid use 1.8%, jaundice 1.2% Group 2: corticosteroid use 1.6%, jaundice 7.2% Inclusion criteria: age > 15 years, with vertical abdominal incisions Exclusion criteria: patients being re‐operated on via an incision made < 1 month previously |
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Interventions |
Comparisons reported: Group 1 Suture: polypropylene (monofilament, non‐absorbable) Suturing technique: interrupted ("figure‐of‐eight, near and far") Closure method: mass Group 2: Sutures: PGA (multifilament, fast absorbable) Suturing technique: interrupted ("figure‐of‐eight, near and far") Closure method: mass Surgeon characteristics: Group 1: consultant/senior resident 56.9%, registrar/senior health officer 43.1% Group 2: consultant/senior resident 56.7%, registrar/senior health officer 43.3% |
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Outcomes |
Incisional hernia: no definition provided Follow‐up duration: 6 months Wound infection: no definition provided Wound dehiscence: complete disruption |
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Notes | Hernia data not included in analysis due to inadequate follow‐up duration | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method to generate allocation sequence not described ("...randomly allocated...") |
Allocation concealment (selection bias) | Low risk | "Patients were randomly allocated to a suture material by the opening of a sealed envelope during the procedure." |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | No information provided |
Incomplete outcome data (attrition bias) All outcomes | High risk | High loss to follow‐up (33/167 in group 1, 49/180 in group 2) |
Selective reporting (reporting bias) | Low risk | There was no evidence of selective reporting |
Other bias | Low risk | The study appears to be free of other sources of bias |