Skip to main content
. 2017 Nov 3;2017(11):CD005661. doi: 10.1002/14651858.CD005661.pub2

Cameron 1980.

Methods RCT
Methods to control for contributory patient factors: none described
Participants Age: not reported
Gender:
Group 1: 54.5% female
Group 2: 51.1% female
Type of incision:
Group 1: midline 34.1%, paramedian 65.9%
Group 2: midline 34.4%, paramedian 65.6%
Type of surgery:
 Group 1: emergency 17.4%
Group 2: emergency 22.2%
Contamination classification of included participants:
 Group 1: contaminated 7.2%
Group 2: contaminated 10.5%
Pre‐operative antibiotic use: no information provided
Prognostic patient factors:
 Group 1: corticosteroid use 1.8%, jaundice 1.2%
Group 2: corticosteroid use 1.6%, jaundice 7.2%
Inclusion criteria: age > 15 years, with vertical abdominal incisions
Exclusion criteria: patients being re‐operated on via an incision made < 1 month previously
Interventions Comparisons reported:
Group 1
 Suture: polypropylene (monofilament, non‐absorbable)
 Suturing technique: interrupted ("figure‐of‐eight, near and far")
 Closure method: mass
 Group 2:
 Sutures: PGA (multifilament, fast absorbable)
 Suturing technique: interrupted ("figure‐of‐eight, near and far")
 Closure method: mass
Surgeon characteristics:
 Group 1: consultant/senior resident 56.9%, registrar/senior health officer 43.1%
Group 2: consultant/senior resident 56.7%, registrar/senior health officer 43.3%
Outcomes Incisional hernia: no definition provided
Follow‐up duration: 6 months
Wound infection: no definition provided
 Wound dehiscence: complete disruption
Notes Hernia data not included in analysis due to inadequate follow‐up duration
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method to generate allocation sequence not described ("...randomly allocated...")
Allocation concealment (selection bias) Low risk "Patients were randomly allocated to a suture material by the opening of a sealed envelope during the procedure."
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk No information provided
Incomplete outcome data (attrition bias) 
 All outcomes High risk High loss to follow‐up (33/167 in group 1, 49/180 in group 2)
Selective reporting (reporting bias) Low risk There was no evidence of selective reporting
Other bias Low risk The study appears to be free of other sources of bias