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. 2017 Nov 3;2017(11):CD005661. doi: 10.1002/14651858.CD005661.pub2

Derzie 2000.

Methods RCT
Methods to control for contributory patient factors: none described
Participants Age: no information provided
Gender: no information provided
Types of incisions: no information provided
Type of surgery:
 Group 1: Roux‐en‐Y gastric bypass 83.1%, vertical banded gastroplasty 2.3%, revision procedures 14.5%, additional cholecystectomy 14.0%
 Group 2: Roux‐en‐Y gastric bypass 84.3%, vertical banded gastroplasty 6.9%, revision procedures 8.8%, additional cholecystectomy 13.8%
Contamination classification of included participants: no information provided
Preoperative antibiotic use: all participants received either cefazolin or gentamicin and vancomycin (if allergic to penicillins)
Prognostic patient factors: all participants were morbidly obese
Inclusion criteria: none described
Exclusion criteria: none described
Interventions Comparisons reported:
Group 1:
 Sutures: nylon (in first 196 participants randomised), PDS (in the last 135 participants randomised)
 Suturing technique: continuous
 Closure method: mass
 Group 2:
 Sutures: nylon (in first 196 participants), PDS (in the last 135 participants)
 Suturing technique: interrupted, "figure‐of‐8"
 Closure method: mass
Surgeon characteristics: no information provided
Outcomes Incisional hernia: not measured
Wound infection: local or systemic inflammation and collection of purulent subcutaneous fluid from wound
 Deep wound complications: included deep surgical site infections and fascial dehiscence
Notes Follow‐up duration: "All wounds were monitored for 30 postoperative days."
 Dehiscence (n = 2) were not separated from "wound complications". All "wound complications" analysed as wound infection
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk "All patients were randomised by odd or even medical record number at the time of fascial closure to either continuous or interrupted fascial closure."
Allocation concealment (selection bias) Unclear risk Not described
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Not clearly reported
Selective reporting (reporting bias) Low risk There was no evidence of selective reporting
Other bias Low risk The study appears to be free of other sources of bias