Goligher 1975.
Methods |
RCT Methods to control for contributory patient factors: none |
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Participants |
Age: Group 1: < 60 years 66.4%, 60‐80 years 31.8%, > 80 years 1.9% Group 2: < 60 years 64.5%, 60‐80 years 33.6%, > 80 years 1.9% Group 3: < 60 years 61.8%, 60‐80 years 35.5%, > 80 years 2.7% Gender: Group 1: 45.8% female Group 2: 32.7% female Group 3: 46.3% female Type of incision: all paramedian incisions Type of surgery: all elective procedures Group 1: peptic ulcer disease 37.3%, colorectal cancer 18.7%, palliative 8.4%, inflammatory bowel disease 22.4%, other 13.1% Group 2: peptic ulcer disease 32.7%, colorectal cancer 23.3%, palliative 6.5%, inflammatory bowel disease 23.3%, other 14.0% Group 3: peptic ulcer disease 36.4%, colorectal cancer 17.2%, palliative 10.0%, inflammatory bowel disease 21.8%, other 14.5% Contamination classification of included participants: Group 1: contaminated 21.5% Group 2: contaminated 30.8% Group 3: contaminated 18.2% Pre‐operative antibiotic use: not described Prognostic patient factors: Group 1: obesity 30.8%, malignancy 27.1%, corticosteroids 8.4% Group 2: obesity 35.5%, malignancy 30.0%, corticosteroids 12.1% Group 3: obesity 40.0%, malignancy 27.3%, corticosteroids 10.0% Inclusion criteria: patients undergoing elective laparotomy through rectus‐displacing paramedian incisions Exclusion criteria: none described |
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Interventions |
Comparisons reported: Group 1 Suture: chromic catgut (monofilament, fast absorbable) Suturing technique: continuous, plus reinforcing interrupted sutures on the anterior rectus Closure method: layered Group 2: Sutures: chromic catgut (monofilament, fast absorbable) plus nylon retention sutures Suture technique: continuous, plus reinforcing interrupted nylon sutures on the anterior rectus Closure method: layered Group 3: Suture: stainless steel (monofilament, non‐absorbable) Suturing technique: interrupted, "figure‐of‐8" sutures Closure method: mass Surgeon characteristics: Group 1: consultant 30.0%, registrar 70.0% Group 2: consultant 30.8%, registrar 66.3%, unknown 2.8% Group 3: consultant 38.2%, registrar 60.0%, unknown 1.8% |
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Outcomes |
Incisional hernia: not defined Follow‐up duration: 6 months Wound infection: not defined Dehiscence: not defined Sinus or fistula: "Persistent wound infection and sinus formation" |
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Notes | Hernia data excluded, due to < 1 year's follow‐up Group 2 excluded from analysis (combined absorbable and non‐absorbable sutures) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Participants followed up for < 1 year for incisional hernia outcomes |
Selective reporting (reporting bias) | Low risk | There was no evidence of selective reporting |
Other bias | Low risk | The study appears to be free of other sources of bias |