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. 2017 Nov 3;2017(11):CD005661. doi: 10.1002/14651858.CD005661.pub2

Irvin 1977.

Methods RCT
Methods to control for contributory patient factors: "The method of randomisation took into account the type of surgery performed..."
Participants Age: unknown
Gender: unknown
Type of incision:
Group 1: median 43.2%, paramedian 56.8%
Group 2: median 40.6%, paramedian 59.4%
Type of surgery:
Group 1: emergent 16.8%, palliative 12.6%; biliary 27.4%, peptic ulcer 30.5%, intestinal 25.3%, other 16.8%
Group 2: emergent 14.6%, palliative 10.4%; biliary 35.4%, peptic ulcer 25.0%, intestinal 20.8%, other 18.8%
Contamination classification of included participants: 163 "clean" wounds, 28 "infected" wounds, not broken down by group
Pre‐operative antibiotic use: not described
Prognostic patient factors: not reported
Inclusion criteria: patients going through exploratory laparotomy through median or paramedian incisions
Exclusion criteria: not described
Interventions Comparisons reported:
Group 1
 Sutures: polypropylene (monofilament, non‐absorbable), polyester retention sutures
 Suturing technique: continuous (with interrupted retention sutures)
 Closure method: layered
 Group 2:
 Sutures: stainless steel (monofilament, non‐absorbable)
 Suturing technique: interrupted, 'figure‐of‐8'
 Closure method: mass
Surgeon characteristics:
Group 1: consultant 40.0%, registrar 60.0%
Group 2: consultant 43.4%, registrar 56.6%
Outcomes Incisional hernia: palpable defect in abdominal fascia with straining
Follow‐up duration: 6 months
Wound dehiscence: no definition provided
Wound infection: discharge of pus from wound
Notes Hernia data excluded from analysis due to inadequate follow‐up duration
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "randomly allocated by drawing a trial card at the end of the abdominal procedure, and the method of randomisation took account of the type of surgery performed…"
Allocation concealment (selection bias) Unclear risk "randomly allocated by drawing a trial card at the end of the abdominal procedure, and the method of randomisation took account of the type of surgery performed…"
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants accounted for and dropouts adequately explained
Selective reporting (reporting bias) Low risk There was no evidence of selective reporting
Other bias Low risk The study appears to be free of other sources of bias