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. 2017 Nov 3;2017(11):CD005661. doi: 10.1002/14651858.CD005661.pub2

Ohira 2015.

Methods RCT
Methods to control for contributory patient factors: unknown
Participants Age: not reported
Gender:
Group 1: female 7.1%
Group 2: female 44.4%
Types of incisions: all incisions were midline
Types of surgery: all elective surgery
Group 1: gastric 53.5%; colon 46.5%
Group 2: gastric 55.6%; colon 44.4%
Contamination classification of included participants: not reported
Preoperative antibiotic use: not reported
Prognostic patient factors:
Group 1: diabetes 10.7%; average BMI 21.7
Group 2: diabetes 25.9%; average BMI 22.0
Inclusion criteria: gastric or colon cancer patients operated on with curative intent, aged 20‐80 years
Exclusion criteria: non curative surgery, previous midline incision, laparoscopic
surgery; immunosuppression (as defined by long‐term corticosteroid use, uncontrolled diabetes, or cirrhosis of the liver); and the surgeon’s judgment that the patient was unsuitable for the trial.
Interventions Comparisons reported:
Group 1:
 Sutures: polyglactin (multifilament, fast absorbable)
 Suture technique: interrupted
 Closure method: mass closure
Group 2:
 Sutures: PDS (monofilament, slowly absorbable)
 Suture technique: interrupted
 Closure method: mass closure
Outcomes Hernia: physical exam, CT scan every 6 months; follow‐up: up to 36 months (minimum 12 months)
Wound Infection: not defined
Dehiscence: not defined
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomisation sequence not clearly described
Allocation concealment (selection bias) Unclear risk Allocation concealment not clearly described
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Blinding of outcome assessors not clearly stated
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants accounted for
Selective reporting (reporting bias) Low risk There was no evidence of selective reporting
Other bias High risk Participants not similar at baseline (higher proportion of women in group 2, 2 vs 12); curative intent of surgery not determined until after randomisation