Skip to main content
. 2017 Nov 3;2017(11):CD005661. doi: 10.1002/14651858.CD005661.pub2

Osther 1995.

Methods RCT
Methods to control for contributory patient factors: none
Participants Age:
Group 1: median 75
Group 2: median 77
Gender:
Group 1 female 53%; Group 2 56.7%
Types of incisions:
Group 1: median 9%; paramedian 59%; oblique 13%; transverse 19%
 Group 2: median 10.6%; paramedian 53.8%; oblique 11.5%; transverse 23.1%
Types of surgery: not described
Contamination classification of included participants: not described
Preoperative antibiotic use: not described
Prognostic patient factors:
Group 1: malignancy 42%
Group 2: malignancy 47.1%
Inclusion criteria: undergoing laparotomy with ≥ 1 criteria for impaired wound healing including age > 70 years, COPD for at least 10 years, intra‐abdominal malignancy or diffuse peritonitis
Exclusion criteria: appendectomy through an oblique muscle‐splitting incision, laparotomy through a previous scar
Interventions Comparisons reported:
Group 1:
 Sutures: PGA (multifilament, fast absorbable)
 Suture technique: interrupted
 Closure method: mass
 Group 2:
 Sutures: polyglyconate (monofilament, slowly absorbable)
 Suture technique: interrupted
 Closure method: mass
Characteristics of surgeons: not described
Outcomes Hernia: palpable protruding swelling and fascial defect
Follow‐up duration: 10 days, 3 months and 12 months
Wound infection: purulent discharge leading to surgical drainage
Dehiscence: fascial disruption with operative closure necessary
Sinus/fistula: no definition provided
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random numbers using Geigy scientific tables
Allocation concealment (selection bias) Unclear risk Not explicitly described
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Not explicitly described
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants accounted for. Loss to follow‐up described by group
Selective reporting (reporting bias) High risk Dehiscence not reported despite pre‐specified
Other bias Low risk The study appears to be free of other sources of bias