Osther 1995.
Methods |
RCT Methods to control for contributory patient factors: none |
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Participants |
Age: Group 1: median 75 Group 2: median 77 Gender: Group 1 female 53%; Group 2 56.7% Types of incisions: Group 1: median 9%; paramedian 59%; oblique 13%; transverse 19% Group 2: median 10.6%; paramedian 53.8%; oblique 11.5%; transverse 23.1% Types of surgery: not described Contamination classification of included participants: not described Preoperative antibiotic use: not described Prognostic patient factors: Group 1: malignancy 42% Group 2: malignancy 47.1% Inclusion criteria: undergoing laparotomy with ≥ 1 criteria for impaired wound healing including age > 70 years, COPD for at least 10 years, intra‐abdominal malignancy or diffuse peritonitis Exclusion criteria: appendectomy through an oblique muscle‐splitting incision, laparotomy through a previous scar |
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Interventions |
Comparisons reported: Group 1: Sutures: PGA (multifilament, fast absorbable) Suture technique: interrupted Closure method: mass Group 2: Sutures: polyglyconate (monofilament, slowly absorbable) Suture technique: interrupted Closure method: mass Characteristics of surgeons: not described |
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Outcomes |
Hernia: palpable protruding swelling and fascial defect Follow‐up duration: 10 days, 3 months and 12 months Wound infection: purulent discharge leading to surgical drainage Dehiscence: fascial disruption with operative closure necessary Sinus/fistula: no definition provided |
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Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Random numbers using Geigy scientific tables |
Allocation concealment (selection bias) | Unclear risk | Not explicitly described |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not explicitly described |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All participants accounted for. Loss to follow‐up described by group |
Selective reporting (reporting bias) | High risk | Dehiscence not reported despite pre‐specified |
Other bias | Low risk | The study appears to be free of other sources of bias |