Trimbos 1992.
| Methods |
RCT Methods to control for contributory patient factors: none |
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| Participants |
Age: Group 1 (mean): 50 Group 2 (mean): 51 Gender: all participants female Types of incisions: all participants with midline incision Types of surgery: not described Contamination classification of included participants: Group 1: clean 40%, clean‐contaminated 58%, contaminated 2% Group 2: clean 34%, clean‐contaminated 64%, contaminated 2% Preoperative antibiotic use: not described Prognostic patient factors: Group 1: diabetes 7%, obesity 50%, malignancy 45%, corticosteroids 5%, other immunosuppression 14%, chronic pulmonary conditions 5% Group 2: diabetes 6%, obesity 45%, malignancy 51%, corticosteroids 5%, other immunosuppression 14%, chronic pulmonary conditions 3% Inclusion criteria: women undergoing midline laparotomy Exclusion criteria: none specified |
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| Interventions |
Comparisons reported: Group 1: Sutures: polyglyconate (monofilament, slowly absorbable) Suture technique: continuous Closure method: layered Group 2: Sutures: polyglactin‐910 (multifilament, fast absorbable) Suture technique: interrupted Closure method: layered Characteristics of surgeons: not described |
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| Outcomes |
Hernia: swelling in the scar with increased intra‐abdominal pressure Follow‐up duration: 12 months Wound infection: purulent discharge from wound or wound fluid containing pathogenic microbes on culture Dehiscence: not defined Sinus or fistula: not defined |
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| Notes | — | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Not explicitly described |
| Allocation concealment (selection bias) | Unclear risk | Not explicitly described |
| Blinding (performance bias and detection bias) All outcomes | Low risk | Outcome assessor blinded |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | All participants accounted for and analysed |
| Selective reporting (reporting bias) | Low risk | Hernia follow‐up at least 1 year; wound infection and dehiscence reported |
| Other bias | Low risk | The study appears to be free of other sources of bias |