Gasparovic 2014.

Methods	Randomized controlled trial.
Participants	Adults scheduled to elective primary CABG. On postoperative day 4, people underwent an aggregometry‐based assessment of their on‐aspirin platelet reactivity. People found to be aspirin‐resistant were randomised into either the control or intervention group.
Interventions	Clopidogrel 75 mg plus aspirin 300 mg (n = 112; mean age (± SD) 65 ± 8 years; male sex 83%) for 6 months. Aspirin 300 mg (n = 110; mean age (± SD) 65 ± 9 years; male sex 82%) for 6 months.
Outcomes	Primary: MACCEs at 6 months (composite outcome including all‐cause mortality, non‐fatal MI, cerebrovascular accident and cardiovascular rehospitalization). Secondary: bleeding events components (Bleeding Academic Research Consortium definitions) and individual MACCE components (BARC type 3, 4 and 5 bleeding events as major bleeding, BARC type 1 and 2 as minor bleeding).
Notes	Prospective randomised study that selectively implemented DAPT after CABG in people with aggregometry‐documented aspirin resistance.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomization software used for participant allocation into the control or intervention arms.
Allocation concealment (selection bias)	Low risk	Randomization software used for participant allocation into the control or intervention arms.
Blinding (performance bias and detection bias) All outcomes	High risk	Prospective randomised study. Single centre without placebo control.
Incomplete outcome data (attrition bias) All outcomes	Low risk	6‐month follow‐up completed in 107 (97%) participants in aspirin monotherapy group and 112 (98%) in DAPT group.
Selective reporting (reporting bias)	Low risk	Reported as per protocol.
Other bias	Unclear risk	No data on funds.