Sayyah‐Melli 2007.

Methods	Single centre (Iran), parallel group RCT. Number of women randomised: N = 50. No withdrawals. No power calculation for sample size reported. Source of funding: not reported.
Participants	Inclusion criteria: women with uterine myoma nodules > 5 cm in diameter with irregular menstrual cycle and candidates for myomectomy. Exclusion criteria: > 40 years of age, abnormal uterine pathology, infection, hypersensitivity to any ergot alkaloids, hepatic and renal disorders, history of toxemia of pregnancy, cardiovascular disease, peptic ulcer, taking antipsychotic medications. Mean age: 30 and 32 years. Recruited from Alzahra University Hospital, Tabriz, Iran.
Interventions	GnRHa (Diphereline 3.75 mg 4 times every 28 days), N = 25 Dopamine agonist (Cabergoline 0.5 mg once/week for 6 weeks), N = 25
Outcomes	Reduction in fibroid volume, symptoms, adverse effects.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"...assigned randomly" but no method reported.
Allocation concealment (selection bias)	Unclear risk	Not reported.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Blinding not reported and highly unlikely because of different administration of intervention regimens (injection and tablet).
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Blinding not reported and unlikely.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No reported withdrawals.
Selective reporting (reporting bias)	Low risk	All prespecified outcomes fully reported.
Other bias	Low risk	Groups appeared comparable at baseline.