Table 2.
Microscopic evaluation after the 30th day of experiment: wounds on the right ear compared to the left ear, regardless of the concentration of the medication
| Comparisons DXE | N | Mean | Standard Deviation | Mean Difference | 95% CI | P Value | P Value |
|---|---|---|---|---|---|---|---|
| Thickness of normal dermis (µm) D | 40 | 377.52 | 64.56 | 1.67 | -30.15 | 33.49 | 0.916 |
| Thickness of normal dermis (µm) E | 40 | 375.85 | 107.82 | ||||
| Scar length (µm) D | 40 | 9252.23 | 1519.77 | 275.44 | -360.41 | 911.29 | 0.386 |
| Scar length (µm) E | 40 | 8976.79 | 1474.14 | ||||
| Scar thickness (µm) D | 40 | 656.59 | 226.94 | -273.07 | -419.09 | -127.05 | 0.001 |
| Scar thickness (µm) E | 40 | 929.66 | 505.25 | ||||
| Capillary concentration D | 40 | 32.05 | 8.34 | 2.60 | -1.63 | 6.83 | 0.221 |
| Capillary concentration E | 40 | 29.45 | 9.94 | ||||
| Lymphocyte concentration D | 40 | 61.78 | 37.65 | -17.70 | -32.69 | -2.71 | 0.022 |
| Lymphocyte concentration E | 40 | 79.48 | 37.77 | ||||
| Presence of neutrophils D | 40 | 4.00 | 5.68 | -4.93 | -8.41 | -1.44 | 0.007 |
| Presence of neutrophils E | 40 | 8.93 | 11.39 | ||||
| Presence of eosinophils D | 40 | 4.15 | 11.14 | -49.45 | -97.44 | -1.46 | 0.044 |
| Presence of eosinophils E | 40 | 53.60 | 149.27 | ||||
| Presence of granulomas D | 40 | 0.55 | 0.90 | -0.13 | -0.55 | 0.30 | 0.560 |
| Presence of granulomas E | 40 | 0.68 | 1.00 | ||||
| Presence of macrophages D | 40 | 22.13 | 35.58 | -14.30 | -34.23 | 5.63 | 0.155 |
| Presence of macrophages E | 40 | 36.43 | 50.69 |
D: Tacrolimus group
E: Control group