| Methods |
A randomised controlled trial |
| Participants |
35 infertile CC‐resistant women with PCOS were prospectively randomised in 2 groups and evaluated from January 2000 through January 2004. Conducted in Suleyman Demireal University Hospital, Isparta, Turkey |
| Interventions |
17 women underwent laparoscopic ovarian drilling with a multi‐needle intervention( LOMNI) and 18 women received step‐up ovulation induction treatment with recombinant FSH for ovulation induction in addition to intrauterine insemination |
| Outcomes |
Cycle regularity, pregnancy rate, OHSS and cost |
| Notes |
Funding source: Not stated
Declarations of interest: Not stated. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
"Computer generated random sequence" |
| Allocation concealment (selection bias) |
Low risk |
Allocated using "sealed opaque envelopes" prior to their surgery |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Not stated but not possible with study design |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Not stated |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Although 1 woman in the LOMNI group and 2 women in the ovulation induction group were lost to follow‐up, their pregnancy results were available and they all received telephone interviews at the end of the follow‐up period |
| Selective reporting (reporting bias) |
Low risk |
None detected |
| Other bias |
Low risk |
None detected |
