Comparison 1.
Slow versus fast heparin injections
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Intensity of injection pain | 3 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 1.1 Immediately after each injection | 2 | 140 | Mean Difference (IV, Random, 95% CI) | ‐1.52 [‐3.56, 0.53] |
| 1.2 48 hours after injection | 2 | 59 | Mean Difference (IV, Random, 95% CI) | ‐1.68 [‐2.91, ‐0.45] |
| 1.3 60 hours after injection | 1 | 40 | Mean Difference (IV, Random, 95% CI) | ‐1.0 [‐2.15, 0.15] |
| 1.4 72 hours after injection | 1 | 40 | Mean Difference (IV, Random, 95% CI) | ‐0.8 [‐1.70, 0.10] |
| 2 Bruise size 48 hours after injection | 4 | 459 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.60 [‐1.24, 0.04] |
| 2.1 Bruise size (mm2) | 2 | 140 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.30 [‐0.64, 0.03] |
| 2.2 Bruise size (mm) | 2 | 319 | Std. Mean Difference (IV, Random, 95% CI) | ‐1.69 [‐5.07, 1.70] |
| 3 Bruise size | 2 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 3.1 60 hours after injection (mm2) | 1 | 40 | Mean Difference (IV, Fixed, 95% CI) | ‐3.85 [‐8.99, 1.29] |
| 3.2 72 hours after injection (mm2) | 2 | 140 | Mean Difference (IV, Fixed, 95% CI) | ‐2.29 [‐6.57, 1.99] |