Kopp 2007.
Methods | Randomised trial of outpatients of a hospital in Berlin, Germany 3 treatment arms: CBZ, LEV, VPS |
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Participants | Newly diagnosed ("de novo") participants Number randomised: CBZ = 6, LEV = 6, VPS = 3 12 (80%) partial epilepsy No information on age or gender |
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Interventions | Monotherapy with CBZ, LEV or VPS Doses started or achieved not stated Assessments performed at 6 and 12 weeks |
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Outcomes | Cognitive performance Neuropsychological assessment |
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Notes | Abstract only. Trial authors could not be contacted to request IPD | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Treatments were "randomly assigned", no further information provided |
Allocation concealment (selection bias) | Unclear risk | No information provided |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | No information provided |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No information provided |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Abstract only, attrition rate not stated. Insufficient information to make a judgement |
Selective reporting (reporting bias) | Unclear risk | Abstract only, insufficient information to make a judgement |
Other bias | Low risk | None identified |