1 chronic.mp.Multimedia(41469) 1193893 2 ((persistent or long* term or ongoing or degenerative) adj3 (disease* or ill* or condition* or insufficienc* or disorder*)).tw.Multimedia(964) 47182 3 long term care/Multimedia(791) 86414 4 long* term care.tw.Multimedia(42583) 16373 5 exp cardiovascular disease/Multimedia(1325) 2892644 6 (heart disease* or heart failure or myocardial ischemia or coronary disease* or coronary artery disease* or myocardial infarction or hypertension or high blood pressure).tw.Multimedia(11507) 822423 7 sickle cell.mp.Multimedia(745) 28624 8 exp chronic obstructive lung disease/Multimedia(3138) 68712 9 (obstructive lung disease* or obstructive pulmonary disease* or copd or asthma or bronchitis).tw.Multimedia(0) 206623 10 lung emphysema/ or emphysema/Multimedia(4273) 26391 11 emphysema.tw.Multimedia(27099) 22105 12 (cystic fibrosis or respiratory distress).mp.Multimedia(14905) 117951 13 ("degenerative disease/" and "exp cerebrovascular disease/").mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]Multimedia(1304) 0 14 (brain adj (disease* or damage* or injur*)).tw.Multimedia(69) 70039 15 (cerebrovascular or brain ischemia or cerebral infarction or carotid artery disease* or stroke or epilep* or seizure*).tw.Multimedia(13394) 417021 16 (neurodegenerative or Huntington* or Parkinson* or amyotrophic lateral sclerosis or multiple sclerosis or motor neuron disease).tw.Multimedia(1200) 216767 17 (paralys* or quadriplegi* or tetraplegi* or paraplegi* or locked‐in syndrome).tw.Multimedia(1768) 63002 18 ((communication or learning or consciousness or perceptual or speech or voice or vision or hearing or psychomotor) adj disorder*).tw.Multimedia(17946) 8558 19 (hearing loss or hearing aid* or deaf* or blind* or stutter*).tw.Multimedia(1599) 335955 20 down* syndrome.tw.Multimedia(32938) 20827 21 cerebral palsy.tw.Multimedia(16626) 18883 22 exp gastrointestinal diseases/Multimedia(13895) 63741 23 (gastroenter* or intestinal or bowel or colonic).tw.Multimedia(2692) 432591 24 kidney failure/Multimedia(7815) 99730 25 ((renal or kidney) adj (failure* or insufficienc*)).tw.Multimedia(12246) 121257 26 exp diabetes mellitus/Multimedia(181990) 567599 27 (diabetes or diabetic*).tw.Multimedia(5638) 535423 28 exp nutritional disorder/Multimedia(6911) 536110 29 (underweight or malnutrition or malnourished or overweight or obes*).tw.Multimedia(6437) 272692 30 exp arthritis/Multimedia(39318) 329119 31 (arthritis or osteoarthritis or rheumati* or fibromyalgia).tw.Multimedia(3378) 244558 32 ((back or neck) adj pain).tw.Multimedia(541500) 43381 33 exp thyroid disease/Multimedia(1618) 171643 34 thyroid.tw.Multimedia(1088) 160664 35 exp hypersensitivity/Multimedia(2033) 459735 36 (hypersensitivit* or allerg* or intolerance or anaphyla*).mp.Multimedia(1245) 415671 37 exp neoplasm/Multimedia(121) 3319359 38 (cancer* or oncolog* or neoplasm* or carcinom* or tumo?r* or malignan* or leuk?emia).tw.Multimedia(585) 2861707 39 exp Human immunodeficiency virus infection/Multimedia(3406) 296469 40 (hiv infect* or hiv disease*).tw.Multimedia(93687) 94757 41 exp mental disease/Multimedia(1043) 1504884 42 ((mental* or psychiatr* or psychological*) adj (ill* or disorder* or disease* or distress* or disab* or problem* or health* or patient* or treatment)).tw.Multimedia(13857) 218664 43 ((personality or mood or dysthymic or cognit* or anxiety or stress or eating or adjustment or reactive or somatoform or conversion or behavior or perception or psycho* or impulse control or development* or attention deficit or hyperactivity or conduct or motor skills or movement or tic or substance related) adj disorder*).tw.Multimedia(25768) 146882 44 (psychos#s or psychotic* or paranoi* or schizo* or neuros#s or neurotic* or delusion* or depression or depressive or bipolar or mania or manic or obsessi* or compulsi* or panic or phobic or phobia or anorexia or bulimia or neurastheni* or dissociative or autis* or Asperger* or Tourette or dyslex* or affective or borderline or narcissis* or suicid* or self injur* or self harm or adhd).tw.Multimedia(99) 723209 45 (((substance or drug or alcohol) adj abuse) or "substance use" or "illegal drug use" or addict* or alcoholism or (problem* adj1 drinking)).tw.Multimedia(315) 142653 46 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36 or 37 or 38 or 39 or 40 or 41 or 42 or 43 or 44 or 45Multimedia(108) 11136325 47 patient care planning/Multimedia(135) 26543 48 ((care or action or treatment) adj plan*).tw.Multimedia(693) 61446 49 decision making/Multimedia(0) 133248 50 (patient* adj7 (decision* or choice*)).tw.Multimedia(0) 62144 51 patient preference/Multimedia(20) 3624 52 (patient* adj3 (preference* or priorit* or value*)).tw.Multimedia(0) 49062 53 (treatment adj (option* or choice*)).tw.Multimedia(89) 73666 54 (goal* adj2 (set* or plan*)).tw.Multimedia(0) 5819 55 (patient adj (cent*red or focus*ed or oriented)).tw.Multimedia(50298) 12376 56 personalized medicine/Multimedia(12880) 6173 57 (individuali#e? or individuali#ing or personali#e? or personali#ing or tailor or tailored or tailoring).tw.Multimedia(7255) 99601 58 47 or 48 or 49 or 50 or 51 or 52 or 53 or 54 or 55 or 56 or 57Multimedia(3116) 488955 59 cooperation/Multimedia(13470) 28755 60 (patient* adj3 (participat* or involv*)).tw.Multimedia(219) 73668 61 (negotiat* or agreement or concordan* or cooperat* or co‐operat* or collaborat* or partnership).tw.Multimedia(0) 478234 62 59 or 60 or 61Multimedia(0) 563462 63 58 and 62Multimedia(0) 31136 64 patient participation/Multimedia(0) 16290 65 (patient* adj2 (empower* or activat*)).tw.Multimedia(0) 7200 66 ((shared or joint or informed or collaborative) adj2 decision making).tw.Multimedia(0) 4162 67 ((involv* or participat*) adj3 (choice* or decision*)).tw.Multimedia(0) 8984 68 (decision adj (aid* or support or tool*)).tw.Multimedia(0) 10090 69 patient provider agreement*.tw.Multimedia(0) 9 70 decisional self efficacy.tw.Multimedia(0) 8 71 (personal budget* or direct payment*).tw.Multimedia(0) 171 72 (record access or patient held record*).tw.Multimedia(0) 119 73 ((self management or self care) adj2 support*).tw.Multimedia(0) 1035 74 or/63‐73Multimedia(0) 72116 75 46 and 74Multimedia(0) 38039 76 randomised controlled trial/Multimedia(0) 355130 77 controlled clinical trial/Multimedia(0) 403750 78 single blind procedure/ or double blind procedure/Multimedia(0) 136026 79 crossover procedure/Multimedia(0) 37988 80 random*.tw.Multimedia(0) 845821 81 placebo*.tw.Multimedia(0) 198596 82 ((singl* or doubl*) adj (blind* or mask*)).tw.Multimedia(0) 161143 83 (crossover or cross over or factorial* or latin square).tw.Multimedia(0) 93133 84 (assign* or allocat* or volunteer*).tw.Multimedia(0) 481400 85 or/76‐84Multimedia(0) 1484254 86 75 and 85Multimedia(0) 6811