#1	((chest ADJ6 drain*).mp. OR (chest ADJ6 tube*)).mp. OR (pleural ADJ6 drain*).mp. OR (pleural ADJ6 tube*).mp. OR exp THORAX‐DRAINAGE/ OR drain*.mp. OR exp SUCTION DRAINAGE/ OR exp SURGICAL‐DRAINAGE/ OR (mediastinal ADJ6 drain*).mp. OR (mediastinal ADJ6 tube*).mp. OR exp DRAIN/ OR OR (thoracic ADJ6 drain*).mp. OR (thoracic ADJ6 tube*).mp.
#2	pneumothorax.mp. OR exp PNEUMOTHORAX/ OR (air ADJ6 leak).mp. OR exp HEMATOTHORAX/ OR h?emothorax.mp. OR exp HEMATOPNEUMOTHORAX/ OR h?emopneumothorax.mp. OR exp HYDROTHORAX/ OR hydrothorax.mp. OR hydropneumothorax.mp. OR exp PLEURAL‐ EFFUSION/ OR (pleural ADJ6 effusion).mp. OR (malignant ADJ6 effusion).mp. OR exp CHYLOTHORAX/ OR chylothorax.mp. OR exp PLEURAL‐ EMPYEMA/ OR (pleural ADJ6 empyema).mp. OR exp EMPYEMA/ OR empyema.mp. OR lobectom*.mp. OR (pulmonary ADJ6 resection).mp. OR (pleural ADJ6 disease*).mp. OR exp PLEURA‐DISEASE/ OR (thoracic ADJ6 surgery) OR exp THORAX SURGERY/ OR (diaphragmatic ADJ6 hernia) OR exp DIAPHRAGMATIC‐HERNIA/ OR (bronchopleural ADJ6 fistula).mp. OR exp BRONCHOPLEURAL‐FISTULA/ OR exp THORACOSCOPY/ OR thoracoscopy.mp. OR video ADJ6 assisted ADJ6 thoracic ADJ6 surgery.mp. OR VATS.mp. OR (cardiac ADJ6 surgery).mp. OR exp HEART‐SURGERY/ OR (heart ADJ6 surgery).mp. OR myocard*.mp. OR pericard*.mp. OR cardiac.mp. OR exp HEART/ OR heart.mp.
#3	exp SUCTION/ OR suction*.mp. OR vacuum.mp. OR exp VACUUM/ OR pressure*.mp. OR exp PRESSURE/
#4	#1 AND #2 AND #3
#5	(RANDOMIZED‐CONTROLLED‐TRIAL/ or RANDOMIZATION/ or CONTROLLED‐STUDY/ or MULTICENTER‐STUDY/ or PHASE‐3‐CLINICAL‐TRIAL/ or PHASE‐4‐CLINICAL‐TRIAL/ or DOUBLE‐BLIND‐PROCEDURE/ or SINGLE‐BLIND‐PROCEDURE/ or (RANDOM* or CROSS?OVER* or FACTORIAL* or PLACEBO* or VOLUNTEER*).ti,ab. or ((SINGL* or DOUBL* or TREBL* or TRIPL*) adj3 (BLIND* or MASK*)).ti,ab.) and human*.ec,hw,fs.
#6	#4 and #5
mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name ti = title ab = abstract ec = EMBASE section heading hw = heading word fs = floating subheading