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. 2013 Nov 27;2013(11):CD008927. doi: 10.1002/14651858.CD008927.pub2

Comparison 5. Polyclonal antibody versus interleukin‐2 receptor antagonist.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Mortality 3 100 Risk Ratio (M‐H, Random, 95% CI) 1.41 [0.54, 3.70]
1.1 Basiliximab 1 24 Risk Ratio (M‐H, Random, 95% CI) 0.39 [0.02, 8.69]
1.2 Daclizumab 2 76 Risk Ratio (M‐H, Random, 95% CI) 1.62 [0.58, 4.46]
2 Acute rejection 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
2.1 Daclizumab 2 76 Risk Ratio (M‐H, Random, 95% CI) 1.35 [0.94, 1.94]
3 Adverse events 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
3.1 Daclizumab 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
4 Infection 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4.1 Basiliximab 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
5 Pneumonia 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
5.1 Daclizumab 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
6 CMV infection 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
6.1 Daclizumab 2 76 Risk Ratio (M‐H, Random, 95% CI) 0.69 [0.17, 2.88]
7 Bronchiolitis obliterans syndrome 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
7.1 Daclizumab 2 76 Risk Ratio (M‐H, Random, 95% CI) 1.70 [0.42, 6.79]
8 Post‐transplantation lymphoproliferative disease (PTLD) 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
8.1 Daclizumab 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
9 Cancer 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
9.1 Daclizumab 1   Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]