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. 2017 Dec 14;2017(12):CD009789. doi: 10.1002/14651858.CD009789.pub2

1. Antioxidant supplements tested in the included trials.

Study ID Antioxidant (type: Ex; Vit; Whole)* Dose** Form taken Regimen Started: before exercise Duration
Arent 2010 Ex: black tea extract; theaflavin 700 mg/day Capsule 4 capsules daily 9 days 11 days
Avery 2003 Vit: vitamin E 992 mg (1200 IU)/day Capsule Not known (daily) 21 days 31 days
Bailey 2011 Ex: mixed supplement: vitamins C, E, B6, B9, B12 and zinc 400 mg vitamin C
 268 mg vitamin E
 etc Capsule 1 capsule daily 42 days 6 weeks
Beaton 2002a Vit: vitamin E 1200 IU Capsule ? 30 days 30 days
Bell 2015 Whole: tart cherry 9.2 mg/mL anthocyanins Drink 30 mL twice daily 3 days 8 days
Bell 2016 Whole: tart cherry 73.5 mg/L total anthocyanin content Drink 30 mL twice daily 4 days 7 days
Bloomer 2004 Vit: vitamin C, E and selenium 268 mg vitamin E
1 g vitamin C
90 µg selenium
Capsule 3 capsules daily 14 days 18 days
Bloomer 2005 Ex: astaxanthin 4 mg astaxanthin
480 mg lutein
Capsule 2 capsules daily 21 days 25 days
Bloomer 2007 Vit: vitamin C and E 1000 mg of vitamin C
378 mg vitamin E
Capsule 2 capsules daily 14 days 14 days
Bryer 2006 Vit: vitamin C 3 g/day vitamin C Capsule 3 capsules daily 14 days 18 days
Close 2006 Vit: vitamin C 1 g/day vitamin C ? ? 0 days (day of exercise) 14 days
Cobley 2011 Ex: N‐acetyl‐cysteine 50 mg/kg/day Powder dissolved in water 50 mg/kg/day once daily dissolved in 500 mL water 1 hour 6 days
Connolly 2006 Vit: vitamin C 1 g/day vitamin C Capsule 3 capsules daily 3 days 8 days
Connolly 2006a Whole: cherry 600 mg phenolic compounds
40 mg anthocyanins
Drink 2 x 12 oz bottle daily 4 days 8 days
Drobnic 2014 Ex: curcumin 400 mg/day curcumin Capsule 2 capsules daily 2 days 5 days
Goldfarb 2011 Ex: Juice Plus powder 7.5 mg beta‐carotene
276 mg vitamin C
 108 IU of vitamin E
Capsule 6 capsules daily 4 days 8 days
He 2015 Vit: vitamin C and vitamin E 100 mg of vitamin C
268 mg (400 IU) of vitamin E
Capsule ? 14 days 17 days
Herrlinger 2015 Ex: black and green tea High‐dose = 2000 mg per
 day polyphenolic blend
Low‐dose = 1000 mg per day polyphenolic blend
Capsule 4 capsules daily 91 days 91 days
Howatson 2009 Whole: cherry 600 mg phenolic compounds expressed as gallic acid equivalents, 32 g of carbohydrate and at least 40 mg of anthocyanins Drink 2 x 8 fl oz bottles per day 5 days 7 days
Hutchinson 2016 Whole: blackcurrant nectar 193.25 mg/day of malvidin glucosides
175.69 mg/day of cyanidin glucosides
Drink 16 oz bottle per day 8 days 8 days
Kaminski 1992 Vit: vitamin C 1 g/day vitamin C Capsule 3 capsules daily 3 days 10 days
Kerksick 2009 Ex: N‐acetyl‐cysteine and epigallocatechin gallate (EGCG) 1800 mg/day N‐acetyl‐cysteine (NAC)
1800 mg/day epigallocatechin gallate (EGCG)
Drink ? 14 days 14 days
Krotkiewski 1994 Ex: pollen extract 30,000 units per gram of Polbax ? ? 28 days 28 days
Kuehl 2010 Whole: cherry 600 mg phenolic compounds
40 mg anthocyanins
Drink 2 x 335 mL bottles daily 7 days 15 days
Laupheimer 2014 Ex: resveratrol 600 mg/day of resveratrol Capsules 6 capsules daily 7 days 9 days
Lynn 2015 Whole: bilberry juice Total phenol content per 200 mL serving was 744.14 ± 81.75 mg (n = 3) and 80.04 ± 3.51 mg (n = 3) of total anthocyanins Drink 2 x 200 mL daily 5 days 8 days
McBride 1997 Vit: vitamin E 992 mg/day of vitamin E (1200 IU) Capsules 1 capsule daily 14 days 14 days
McCormick 2016 Whole: cherry 9.117 mg/mL anthocyanins Drink 90 mL daily (2 x 30 mL) 6 days 6 days
McFarlin 2016 Ex: curcumin 400 mg/day curcumin Capsules Capsules 2 days 6 days
McLeay 2012 Whole: blueberry smoothie Per 100 mL: total phenolics 168 mg/gallic acid equ.; anthocyanins 96.6 mg; phenolic acid 26 mg,
 flavonoids 10.2 mg; vitamin C 45 mg; vitamin E 3 mg Drink 200 g blueberries, 50 g banana + 200 mL apple juice daily 0 days (day of exercise) 4 days
Meamarbashi 2011 Ex: purslane extract 1200 mg/day purslane extract Capsules 2 capsules daily 3 days 5 days
Michailidis 2013 Vit: N‐acetyl‐cysteine 20 mg/kg/day N‐acetyl‐cysteine Drink 3 x 500 mL drink daily 0 days (day of exercise) 9 days
Nicol 2015 Ex: curcumin 2.5 g/day of curcumin Capsules 10 capsules daily (2 x 5 capsules) 2.5 days 5 days
Nie 2004 Vit: vitamin C 800 mg/day vitamin C Capsules ? 3 hours 2 days
O'Connor 2013 Whole: grape juice 1.75 mg/kg resveratrol
19.7 mg/kg catechin
12.6 mg/kg
31.7 mg/kg peonidin
125 mg/kg cyanidin
145.2 mg/kg
32.6 mg/kg quercetin
5.6 mg/kg kaempferol
6.8 mg/kg isorhamnetin
Drink (dissolved powder) 1 serving of powder daily mixed with 236 mL of water 45 days 50 days
O'Fallon 2012 Ex: quercetin 1000 mg/day quercetin Bar 2 bars daily 7 days 7 days
Peschek 2014 Whole: cocoa 350 mg/day flavanols Drink 240 mL daily 0 days (day of exercise) 3 days
Phillips 2003 Ex: mixed antioxidants 300 mg/day tocopherols
800 mg/day docosahexaenoate
300 mg/day flavonoids of which was 100 mg hesperetin and 200 mg quercetin
Capsules Vitamin E: 1 capsule; docosahexaenoate: 3 capsules; flavonoids: 3 capsules 14 days 14 days
Shafat 2004 Vit: vitamin C + vitamin E 500 mg/day vitamin C
992 mg/day (1200 IU/day) vitamin E
Capsules ? ? 37 days
Silva 2008 Ex: N‐acetyl‐cysteine 10 mg/kg/day of body mass N‐acetyl‐cysteine Capsules 1 capsule daily 14 days 21 days
Silva 2010 Vit: vitamin E 536 mg/day (800 IU/day) vitamin E Capsules 1 capsule daily 14 days 21 days
Su 2008 Ex: allicin 80 mg/day allicin Capsules Capsules 14 days 16 days
Tanabe 2015 Ex: curcumin 150 mg/day curcumin Capsules 6 capsules daily 0 days (day of exercise; 1 hour before) 1 day
Theodorou 2011 Vit: vitamin C + vitamin E 1 g/day vitamin C
268 mg/day (1200 IU/day) vitamin E
Capsules 1 capsule daily 28 days 77 days
Thompson 2001 Vit: vitamin C 1 g/day vitamin C Drink ? 0 days (day of exercise; 2 hours before) 1 day
Thompson 2001a Vit: vitamin C 1 g/day of vitamin C on day 1 followed by 400 mg/day divided into 2 doses for 12 days Drink and capsules 1 g given in a solution followed by 400 mg/day doses in capsules 14 days 14 days
Thompson 2003 Vit: vitamin C 200 mg/day vitamin C Drink Daily drink 0 days (day of exercise) 3 days
Thompson 2004 Vit: vitamin C 200 mg/day vitamin C Drink Daily drink 14 days 14 days
Trombold 2010 Whole: pomegranate juice 650 mg/day polyphenols, consisting of 95.5% ellagitannins, 3.5% ellagic acid and 1% anthocyanins Drink 960 mL per day (as 2 x 480 mL drinks) 9 days 32 days
Trombold 2011 Whole: pomegranate juice 3958 mg/L of tannins
768 mg/L anthocyanins
242 mg/L of ellagic derivatives
Drink 500 mL per day (as 2 x 250 mL drinks) 15 days 44 days

* Types: Extract, mixed or other (e.g. amino‐acid derivative) antioxidants; Vitamin; and Whole natural food source.
 ** Every study included in this review used a dose higher than the recommended daily amount.