Bell 2016.
Methods | Double‐blind randomised controlled trial (parallel design) | |
Participants | Setting: laboratory; England n = 16 semi professional male soccer players (8 in the experimental group; 8 in the placebo group) Mean age 25 (SD 4) years Inclusion/exclusion criteria Inclusion criteria required participants to have trained in soccer consistently across the preceding 3 years and be free of any lower limb injury for the preceding 6 months |
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Interventions |
Intervention Participants were instructed to consume 30 mL of the supplement twice per day (0800 and 1800 hours) for 7 consecutive days (4 days pretrial and on each trial day). The supplement was a commercially available Montmorency cherry concentrate (CherryActive, Sunbury, UK); containing a total anthocyanin content of 73.5 mg·L−1 of cyanidin‐3‐glucoside, a total phenolic content of 178.8 gallic acid equivalent·L−1 and an antioxidant capacity (TEAC) of 0.58 trolox equivalents·L−1 Placebo A commercially available, less than 5% fruit, cordial, mixed with water and maltodextrin (MyProtein Ltd, Northwich, UK) until matched for energy content of the intervention (102 kcal) Duration 7 days |
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Outcomes |
PRIMARY Muscle soreness was assessed using a 0 to 200 mm visual analogue scale where 0 is "no pain" and 200 is "unbearably painful". Participants rated their soreness after completing a squat to approximately a 90° knee flexion before standing and immediately marked upon the scale to indicate their level of soreness SECONDARY Maximum voluntary isometric contraction of the dominant knee extensors was determined using a strain gauge (MIE Medical Research Ltd., Leeds, UK). Participants were given standardised verbal encouragement for the duration of each of the 3 maximum 3‐second contractions. Each contraction was separated by 1 minute Sprint performance (20 m ‐ infrared timing gates) Agility: 5‐0‐5 agility test (infrared timing gates) Power: counter movement jump (jump mat) |
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Exercise type | 12 × 20 m run sprints, departing every 60 seconds followed by an adapted version of the Loughborough Intermittent Shuttle Test (LIST) (6 x 15‐minute sections) | |
Sources of funding | The Cherry Marketing Institute (a not for profit organisation) provided financial support for the analysis of inflammatory indices | |
Notes | Authors were contacted on 3 February 2017 to request raw data for delayed onset muscle soreness and maximal voluntary isometric contraction and responded on 3 February 2017 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | No details in manuscript Authors confirmed via email on 3 February 2017 that stratified randomisation based on aerobic fitness and coin toss was employed |
Allocation concealment (selection bias) | Low risk | Manuscript states: "All supplements were prepared by an independent member of the department prepared in opaque bottles in order to maintain the double blind design" |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Double‐blind |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Double‐blind |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No details in manuscript Authors confirmed via email on 3 February 2017 that all participants completed the study |
Selective reporting (reporting bias) | High risk | Delayed onset muscle soreness data immediately post‐exercise not recorded or reported Adverse effects of antioxidant supplementation were not reported |
Other bias | Unclear risk | Manuscript states that participants "were also provided with a diet record diary and a list of foods to avoid throughout the 4 days prior to and during the trial period" No information on NSAIDs or medication |