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. 2017 Dec 14;2017(12):CD009789. doi: 10.1002/14651858.CD009789.pub2

Hutchinson 2016.

Methods Randomised controlled trial (parallel design)
Participants Setting: laboratory; USA
n = 16 college students (24 were originally recruited)
Mean age blackcurrant group (n = 9, 7 female) 19.5 (SEM 0.3) years
Mean age placebo group (n = 8, 6 female) 20.9 (SEM 0.9) years
Inclusion/exclusion criteria
Inclusion criteria included being untrained, moderately active, between the ages of 18 and 40 years. Exclusion criteria included a recent history of ankle, knee, hip or back pain that precluded squatting exercises, and the use of anti‐inflammatory or analgesic drugs that would reduce pain.
Interventions Intervention
Commercially available blackcurrant nectar (CurrantC) was provided by CorpPharms (Staatsburg, NY). Each 16 oz bottle contained approximately 100 g of fruit, malvidin glucosides 193.25 mg, cyanidin glucosides 175.69 mg
Placebo
The placebo drink was produced by mixing black cherry Kool‐Aid powder (Kraft, Ryrerbrook, NY, USA) with water
Duration
8 days
Outcomes Primary
Muscle soreness was assessed during a full range squat with no external weight using a 0 to 10 scale where 0 is "no soreness" and 10 is "extreme discomfort"
Exercise type Eccentric squatting session consisted of 3 sets of 10 repetitions of eccentric contractions using a bar weighted with 115% of the respective 1 repetition maximum
Sources of funding None
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Independent 3rd party completed randomisation using random number generation in Excel
Allocation concealment (selection bias) Unclear risk Not indicated in the manuscript
 Authors contacted on 3 February 2017 but no response was received
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Double‐blind; labels removed from bottles; neither personnel nor participants aware of contents
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Double‐blind
Incomplete outcome data (attrition bias) 
 All outcomes High risk 24 recruited, 16 completed the study (4 illness; 3 injury; 1 removed due to undertaking resistance training prior to study)
Selective reporting (reporting bias) High risk All outcomes reported at all time points
Adverse effects of antioxidant supplementation were not reported
Other bias Low risk Diet not standardised during the trial however participants advised to maintain normal diet and avoid anti‐inflammatory foods and drugs