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. 2017 Dec 14;2017(12):CD009789. doi: 10.1002/14651858.CD009789.pub2

Lynn 2015.

Methods Randomised controlled trial (single‐blind, parallel design)
Participants Setting: field; UK
n = 21 (experimental group of 11, placebo group of 10; 2 participants were excluded from the bilberry group as they failed to report to the lab to provide follow‐up data), recreationally trained runners, age range 18 to 55 years
Inclusion/exclusion criteria
Individuals with cardiovascular disease, diabetes, hypertension, gastrointestinal problems, renal disease, musculoskeletal problems, regular antioxidant or NSAIDs use, and any food allergies were excluded from the study
Interventions Intervention
2 x 200 mL of bilberry juice daily for 5 days before completing the Sheffield Half Marathon, on race day and for 2 days post‐race
Total phenol content per 200 mL serving was 744.14 ± 81.75 mg (n = 3). and 80.04 ± 3.51 mg (n = 3) of total anthocyanins
Placebo
Energy matched control drink
Duration
8 days
Outcomes PRIMARY
Delayed onset muscle soreness, 200 mm visual analogue scale, rated after a squat to a 90 angle and returning to a standing position: 0 "complete absence of pain" to 200 "indicating extreme soreness with noticeable pain and stiffness at all times"
Exercise type Sheffield half marathon
Sources of funding The study was funded by Sheffield Hallam University
Notes 2 x 200 mL of bilberry juice was consumed 5 days before the race, on the day of, and up to 48 hours post race
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk No details in published abstract
Authors confirmed via email on 3 February 2017 that a "random numbers generator" was employed
Allocation concealment (selection bias) Unclear risk No details in published abstract
Authors described via email on 3 February 2017 that the "Study was single blind so investigators knew which drink each participant got" and "drinks were given in non‐labelled container"
Adequate safeguards not reported
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No details in published abstract
Authors described via email on 3 February 2017 that the "Study was single blind so investigators knew which drink each participant got" and "drinks were given in non‐labelled container"
Not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Participants may have remained blinded but this is not confirmed
Incomplete outcome data (attrition bias) 
 All outcomes High risk No details in published abstract
Authors confirmed via email on 3 February 2017 that "Of the 21 participants, we missed getting data from 2, one missed the post race sample, and on the last day one other person was missed ‐ both were in the bilberry group"
Selective reporting (reporting bias) Low risk No published protocol
All data available at all time points
Personal communication: "None of the participants reported any adverse effects from consuming the Bilberry juice or the placebo"
Other bias Low risk Participants were asked to complete a food diary and were asked to refrain from using anti‐inflammatory drugs or other supplements that could reduce soreness