Lynn 2015.
Methods | Randomised controlled trial (single‐blind, parallel design) | |
Participants | Setting: field; UK n = 21 (experimental group of 11, placebo group of 10; 2 participants were excluded from the bilberry group as they failed to report to the lab to provide follow‐up data), recreationally trained runners, age range 18 to 55 years Inclusion/exclusion criteria Individuals with cardiovascular disease, diabetes, hypertension, gastrointestinal problems, renal disease, musculoskeletal problems, regular antioxidant or NSAIDs use, and any food allergies were excluded from the study |
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Interventions |
Intervention 2 x 200 mL of bilberry juice daily for 5 days before completing the Sheffield Half Marathon, on race day and for 2 days post‐race Total phenol content per 200 mL serving was 744.14 ± 81.75 mg (n = 3). and 80.04 ± 3.51 mg (n = 3) of total anthocyanins Placebo Energy matched control drink Duration 8 days |
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Outcomes |
PRIMARY Delayed onset muscle soreness, 200 mm visual analogue scale, rated after a squat to a 90 angle and returning to a standing position: 0 "complete absence of pain" to 200 "indicating extreme soreness with noticeable pain and stiffness at all times" |
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Exercise type | Sheffield half marathon | |
Sources of funding | The study was funded by Sheffield Hallam University | |
Notes | 2 x 200 mL of bilberry juice was consumed 5 days before the race, on the day of, and up to 48 hours post race | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | No details in published abstract Authors confirmed via email on 3 February 2017 that a "random numbers generator" was employed |
Allocation concealment (selection bias) | Unclear risk | No details in published abstract Authors described via email on 3 February 2017 that the "Study was single blind so investigators knew which drink each participant got" and "drinks were given in non‐labelled container" Adequate safeguards not reported |
Blinding of participants and personnel (performance bias) All outcomes | High risk | No details in published abstract Authors described via email on 3 February 2017 that the "Study was single blind so investigators knew which drink each participant got" and "drinks were given in non‐labelled container" Not blinded |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Participants may have remained blinded but this is not confirmed |
Incomplete outcome data (attrition bias) All outcomes | High risk | No details in published abstract Authors confirmed via email on 3 February 2017 that "Of the 21 participants, we missed getting data from 2, one missed the post race sample, and on the last day one other person was missed ‐ both were in the bilberry group" |
Selective reporting (reporting bias) | Low risk | No published protocol All data available at all time points Personal communication: "None of the participants reported any adverse effects from consuming the Bilberry juice or the placebo" |
Other bias | Low risk | Participants were asked to complete a food diary and were asked to refrain from using anti‐inflammatory drugs or other supplements that could reduce soreness |