O'Fallon 2012.

Methods	Randomised controlled trial (parallel design)
Participants	Setting: laboratory, USA n = 30 sedentary adults (15 men and 15 women), age range 18 to 25 years Mean age placebo group men (n = 8) 19.5 (SD 1.1) years, mean age placebo group women (n = 7) 19.6 (SD 1.3) years Mean age supplement group men (n = 7) 20.9 (SD 1.8) years, mean age placebo group women (n = 8) 20.6 (SD 1.1) years Inclusion/exclusion criteria Participants were sedentary to recreationally active, naive to resistance training and resistance‐type activities of the upper extremities for 6 months before participation, negative (by self‐report) for family history of and current musculoskeletal or metabolic impairments, and not taking any dietary supplements
Interventions	Intervention First Strike Nutrition (Natick Soldier Centre, Natick MA) Bars with 1000 mg of Quercitin (Merck, SA Brazil) Placebo Placebo First Strike Nutrition Bar (Natick Soldier Centre, Natick MA) Duration 7 days
Outcomes	PRIMARY Delayed onset muscle soreness was assessed using a 100 mm visual analogue scale where 0 is "no soreness" and 100 is "unbearable pain" Elbow flexor SECONDARY Resting arm angle Upper arm swelling Isometric peak torque
Exercise type	24 eccentric contractions of the elbow flexors
Sources of funding	Funded by the US Army contract # W911QY‐07‐C‐0001
Notes	1 bar twice daily for 7 days Authors were contacted to request raw data for delayed onset muscle soreness, range of motion and maximal voluntary isometric contraction on 3 November 2013 and responded on 3 December 2013
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomly assigned in a permuted block design
Allocation concealment (selection bias)	Unclear risk	No details in the manuscript Authors were contacted but no reply received
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double‐blind
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Double‐blind
Incomplete outcome data (attrition bias) All outcomes	Low risk	All participants completed the study without any adverse effects
Selective reporting (reporting bias)	High risk	No published protocol available All outcomes reported at all time points Adverse effects of antioxidant supplementation were not reported
Other bias	Low risk	Food records were obtained, participants were instructed to minimise foods high in quercetin and were asked to refrain from taking any other supplements, anti‐inflammatory medication or engage in any other modality that could enhance recovery