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. 2016 Mar 17;2016(3):CD010912. doi: 10.1002/14651858.CD010912.pub3
Methods Random allocation by cluster
Unblinded
Study duration: 6 days
Drop outs: 23%
Location: USA
Recruitment: employees with clerical positions were identified through University directory.
Participants Population: full time employees (employed >20 yrs) engaged in a sedentary occupation
Intervention: stand group: 29 participants
step group: 31 participants
Demographics: mean age: stand: 42.3 (SD 11.6) years, step: 46.1 (SD 10.5) years
60% were females in stand group and 75% were females in step group
BMI: Stand: 29.3 (SD 7.3) kg/m², step: 27.7 (SD 7.4) kg/m²
Interventions Duration of intervention: 3 days
Intervention: computer‐based versus wrist worn prompts
Outcomes Outcome name, measurement time/tool (units of measurement)
Total sitting time (minutes/workday), duration of longest sitting bout (minutes/workday), number of sitting bouts/workday of 30 min or more, standing time (minutes/workday), stepping time, sit/stand transitions measured by accelerometer‐inclinometers.
Notes The Clinical and Translational Science Institute of Southeastern Wisconsin supported this research.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random number generation was used to assign participants to either the stand group or step group.
Allocation concealment (selection bias) Low risk Assignments were written out and placed in sealed numbered envelopes.
Blinding of participants and personnel (performance bias) All outcomes High risk The envelopes were opened sequentially by a researcher, participants were informed of group assignment.
Blinding of outcome assessment (detection bias) All outcomes Low risk Since the measurements for sitting were recorded by accelerometer‐inclinometers, it is unlikely that results were influenced by the lack of blinding.
Incomplete outcome data (attrition bias) All outcomes High risk 18 participants were excluded, 9 each from stand group and step group. Reasons were drop out, equipment malfunction and not wearing monitor properly. The authors did not conduct intention‐to‐treat analysis.
Selective reporting (reporting bias) Low risk All outcomes mentioned in the methods section were reported. The study protocol was not available.
Baseline comparability/ imbalance Low risk No baseline differences were found between the two groups for age, body mass, height or BMI.
There was however difference in gender with the Stand group having 60% females and the Step group having 75%.
Validity of outcome measure Low risk The accelerometer is a valid instrument for the measurement of sitting time.