Comparison 50.

Paromomycin 15% + 10% urea (twice daily for 14 d) versus vehicle (twice daily for 14 d)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Participants complete cure	2	383	Risk Ratio (M‐H, Random, 95% CI)	1.00 [0.86, 1.17]
2 Adverse effects	3		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Skin/local reaction	3	463	Risk Ratio (M‐H, Random, 95% CI)	0.94 [0.45, 1.93]
3 Microbiological cure of skin lesions	2	383	Risk Ratio (M‐H, Random, 95% CI)	1.03 [0.88, 1.20]