Study	Reason for exclusion
Alavi‐Naini 2012	Review
Banihashemi 2015	Inclusion criteria of the patients: patients with lupoid leishmaniasis, chronic recurrent leishmaniasis, that typically follows an acute form of cutaneus leishmaniasis
Bumb 2010	Not an RCT. "Selected patients were categorised into two groups (groups A and B) of 110 persons each. Alternate patients were included in group A and B, respectively"
Dogra 1986	They stated that participants were randomly selected for the study, but not randomly assigned to the treatment groups.
Dogra 1994	They stated that participants were randomly selected for the study, but not randomly assigned to the treatment groups.
Dorlo 2012	Review
El On 1992	Cross‐over study
Frankenburg 1993	It measured immunity parameters but did not show any clinical results.
Kim 2009	This was a meta‐analysis.
Moosavi 2005	The method of generation of randomisation was inappropriate. The author was contacted and stated that after enrolling the participants, they did consecutively allocate ILMA for odd number participants and used topical paromomycin for even number participants.
Nilforoushzadeh 2010	They stated that participants were randomly selected for the study, but not randomly assigned to the treatment groups.
Nilforoushzadeh 2011	Included immunocompromised and chronically ill patients
Siavash 2013	Only studied electrocardiogram and biochemical adverse effects of meglumine antimoniate
Singh 1995	They stated that participants in both groups were randomly selected. However, they did not have an initial population eligible for the study that was randomly divided in the 2 treatment groups. But rather one group of people that were randomly selected for one group and another group of participants that were also randomly selected to form part of the other group. Besides, the duration of treatments was not the same and the follow‐up was also different for both treatment groups.
Trau 1987	No clear data is available for multiple lesions. Only lesions from participants with multiple lesions were randomised. The lesions from participants with single lesions a cross‐over study was performed.

RCT: randomised controlled trial.